Elodie Bégué

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To determine whether prenatal corticosteroid therapy would reduce the incidence of neonatal necrotizing enterocolitis (NEC), we assigned a total of 466 women admitted in premature labor either to receive placebo (group A, n = 256), if delivery was expected to occur within 24 hours of admission, or to receive betamethasone (group B, n = 210) if delivery was(More)
PURPOSE A key molecular feature of cutaneous T-cell lymphomas (CTCL) is the constitutive activation of the nuclear factor-kappaB (NF-kappaB) transcription factor. We investigated in vitro the effects on CTCL survival and chemoresistance of a specific inhibition of IkappaB kinase subunit 2 (IKK2). EXPERIMENTAL DESIGN Selective IKK2 inhibition was carried(More)
A molecular feature of Sézary syndrome (SS) is the abnormal expression of T-plastin by malignant T cells. Herein, we investigated the molecular mechanisms involved in T-plastin synthesis and the functions of this actin-binding protein, with a special interest in chemoresistance and migration. We confirm the specific expression of T-plastin in peripheral(More)
Several publications, including ours, reported that T-plastin (PLS3) is specifically expressed in patients with Sézary syndrome (SS), the erythrodermic and leukemic form of cutaneous T-cell lymphoma (CTCL).1-5 Besides PLS3, several other molecular SS-restricted markers, including the transcription factor Twist,6 have been identified by gene expression(More)
To restore facial symmetry in cases of paralyzed lower lip, we have followed the selective neurectomy procedure developed for the lower lip, by Marino [7] and Marino and Alurralde [8]. After cadaveric dissections carried out on 10 facial halves, we demonstrated that several other interconnected branches of the facial nerve innervate the lower lip(More)
A molecular feature of Sézary syndrome (SS) is the abnormal expression of T-plastin by malignant T cells. Herein, we investigated the molecular mechanisms involved in T-plastin synthesis and the functions of this actin-binding protein, with a special interest in chemoresistance and migration. We confirm the specific expression of T-plastin in peripheral(More)
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