Elodie Aubrun

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BACKGROUND To describe the clinical course and treatment patterns over 24 months of patients experiencing an acute manic/mixed episode within the standard course of care. METHODS EMBLEM was a 2-year European prospective, observational study on outcomes of patients experiencing a manic/mixed episode. Adults with bipolar disorder were enrolled within the(More)
The cause of immune thrombocytopenia (ITP) remains unknown. Studies have suggested immunizations as possible triggering factors of ITP through molecular mimicry. This case-control study explored potential associations between adult ITP and various routinely administered vaccines. A network of internal medicine and hematology centers across France recruited(More)
PURPOSE Patients' self-reported drug exposure is subjected to memory errors and different sources of bias. Utilization of prescription records is impaired with non-compliance and over-the-counter (OTC) drug utilization. This study compared patients' self-report (PS) to physician's prescriptions of cardiovascular drugs (CVDs). METHODS The PGRx database is(More)
PURPOSE Patients' self-reported vaccine exposure (PS) may be subject to memory errors and other biases. Physicians' prescription records and other medical records (MR) do not capture noncompliance with vaccination. This study compared PS with MR for influenza, 23-valent pneumococcal, and human papillomavirus (HPV) vaccines. METHODS The(More)
Lamiae Grimaldi-Bensouda,1,2 Marc Michel,3 Elodie Aubrun,1 Pamela Leighton,4 Jean-Francois Viallard,5 Daniel Adoue,6 Nadine Magy-Bertrand,7 Guillaume Tisserand,7 Mehdi Khellaf,3 Jean-Marc Durand,8 Philippe Quittet,9 Olivier Fain,10 Bernard Bonnotte,11 Anne Sophie Morin,10 Nicolas Limal,3 Nathalie Costedoat-Chalumeau,12 Nathalie Morel,12 Brigitte(More)
OBJECTIVE Studies have suggested that systemic lupus erythematosus (SLE) may be triggered by vaccinations. We undertook this study to investigate the relationship between vaccination and onset of SLE. METHODS This international case-control study was conducted between April 2008 and June 2012 in 36 specialist referral centers (34 in France and 2 in(More)
BACKGROUND Evidence on the real effectiveness of statins on acute coronary syndrome (ACS) incidence is scarce. We assessed the effectiveness of real-life statins on the risk of first non-fatal ACS in a low-cardiovascular-risk country. METHODS Systematic case-control study was conducted in 60 cardiology centres and 371 general practices from across France.(More)
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