Elodia B. Cole

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RATIONALE AND OBJECTIVES To compare the diagnostic accuracy of the Fischer Senoscan Digital Mammography System with that of standard screen-film mammography in a population of women presenting for screening or diagnostic mammography. MATERIALS AND METHODS Enrollment of patients took place at six different breast-imaging centers between 1997 and 1999. A(More)
Digital mammography systems allow manipulation of fine differences in image contrast by means of image processing algorithms. Different display algorithms have advantages and disadvantages for the specific tasks required in breast imaging-diagnosis and screening. Manual intensity windowing can produce digital mammograms very similar to standard screen-film(More)
PURPOSE To determine effects of lesion type (calcification vs mass) and image processing on radiologist's performance for area under the receiver operating characteristic curve (AUC), sensitivity, and specificity for detection of masses and calcifications with digital mammography in women with mammographically dense breasts. MATERIALS AND METHODS This(More)
OBJECTIVE The purpose of this study was to compare specificity in the interpretation of calcifications in soft-copy reviewing of digital mammograms versus hard-copy reviewing of screen-film mammograms. MATERIALS AND METHODS A total of 130 consecutive cases with calcifications (44 malignant and 86 benign) that had been evaluated with needle or surgical(More)
RATIONALE AND OBJECTIVES HER-2/neu is a valuable prognostic and therapeutic marker in primary breast carcinoma. The objective of this study was to determine the mammographic and patient characteristics (age) that correlate with HER-2/neu overexpression in primary breast carcinoma. MATERIALS AND METHODS HER-2/neu characteristics and preoperative mammograms(More)
RATIONALE AND OBJECTIVES The aim of this study was to determine if patients who underwent partial-breast irradiation followed by segmental mastectomies had fewer mammographic changes on the first post-treatment mammogram than those who underwent segmental mastectomies followed by whole-breast irradiation. MATERIALS AND METHODS Subjects enrolled in a study(More)
PURPOSE To compare the speed and accuracy of the interpretations of digital mammograms by radiologists by using printed-film versus soft-copy display. MATERIALS AND METHODS After being trained in interpretation of digital mammograms, eight radiologists interpreted 63 digital mammograms, all with old studies for comparison. All studies were interpreted by(More)
RATIONALE AND OBJECTIVES This study was performed to investigate whether full-field digital mammography (FFDM) is at least as accurate as screen-film mammography with respect to breast lesion characterization. MATERIALS AND METHODS Seventy-nine breast surgical specimens were obtained by means of preoperative needle localization with surgical excision from(More)
RATIONALE AND OBJECTIVES Diagnostic mammography is performed on women with clinical symptoms that suggest breast cancer or women for whom further mammographic evaluation has been requested because of an abnormal screening mammography. We assessed whether the use of full-field digital mammography would improve the positive predictive value (PPV) for the(More)
PURPOSE To retrospectively compare the accuracy for cancer diagnosis of digital mammography with soft-copy interpretation with that of screen-film mammography for each digital equipment manufacturer, by using results of biopsy and follow-up as the reference standard. MATERIALS AND METHODS The primary HIPAA-compliant Digital Mammographic Imaging Screening(More)