Eloa S Adams

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Bronchopulmonary dysplasia (BPD), a chronic lung disease of infancy, is characterized by arrested alveolar development. Pulmonary angiogenesis, mediated by the vascular endothelial growth factor (VEGF) pathway, is essential for alveolarization. However, the transcriptional regulators mediating pulmonary angiogenesis remain unknown. We previously(More)
OBJECTIVE Timely provision of evidence-based recommendations through computerized physician order entry with clinical decision support may improve use of red blood cell transfusions (RBCTs). METHODS We performed a cohort study with historical controls including inpatients admitted between February 1, 2008, and January 31, 2010. A clinical decision-support(More)
Previously, we observed that hypoxia increases the expression of the β1-subunit (KCNMB1) of the calcium-sensitive potassium channel (BK(Ca)). Herein, we elucidate the mechanism whereby hypoxia increases KCNMB1 expression in human pulmonary artery smooth muscle cells (hPASMC). In response to hypoxia, the expression of both the transcription factor(More)
OBJECTIVES To test the hypothesis that limits on repeating laboratory studies within computerized provider order entry decrease laboratory utilization. DESIGN Cohort study with historical controls. SETTING A 20-bed PICU in a freestanding, quaternary care, academic children's hospital. PATIENTS This study included all patients admitted to the pediatric(More)
  • Eloa S Adams
  • 2009
OBJECTIVE To review the findings and discuss the implications of transfusion strategies in stable critically ill children. DESIGN A critical appraisal of the article "Transfusion strategies for patients in pediatric intensive care units" by Lacroix J, Hebert PC, Hutchison, et al, published in the N Engl J Med in 2007 with literature review. FINDINGS In(More)
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