Ellison Bentley

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OBJECTIVE To determine if systemic administration of lidocaine during intraocular surgery reduces post-operative ocular pain. STUDY DESIGN Randomized, masked, controlled experimental trial. ANIMALS Twelve dogs weighing 15.5 +/- 1.7 kg (mean +/- SD) and aged 2.5 +/- 0.6 years. METHODS All dogs underwent a baseline ophthalmic examination and subjective(More)
PURPOSE Keratoconjunctivitis sicca (KCS) is characterized by inflammation and decreased production of tears containing increased levels of cytokines. The release occurs in the setting of conjunctival and lacrimal gland inflammation, potentially mediated by the interaction between lymphocyte function-associated antigen (LFA)-1, a cell surface protein found(More)
OBJECTIVE To assess the refractive state of eyes in various breeds of dogs to identify breeds susceptible to ametropias. ANIMALS 1,440 dogs representing 90 breeds. PROCEDURES In each dog, 1 drop of 1% cyclopentolate or 1% tropicamide was applied to each eye, and a Canine Eye Registration Foundation examination was performed. Approximately 30 minutes(More)
OBJECTIVE To test the hypothesis that radiography of the lumbar spine in patients with low back pain is not associated with improved clinical outcomes or satisfaction with care. DESIGN Randomised unblinded controlled trial. SETTING 73 general practices in Nottingham, north Nottinghamshire, southern Derbyshire, north Lincolnshire, and north(More)
OBJECTIVE To develop and compare 3 techniques for retrobulbar injection of local anesthetic agents for ocular surgery and analgesia in dogs. DESIGN Prospective study. ANIMALS 17 dogs (including 9 cadavers). PROCEDURES Inferior-temporal palpebral (ITP), perimandibular, and combined superior-inferior peribulbar injection techniques were compared by(More)
The purpose of this study was to determine the inhibitory effect of selenocystamine coated intraocular lenses (IOLs) on the formation of posterior capsule opacification (PCO) in an ex vivo canine lens capsular bag assay. Selenocystamine was covalently bound to the surface of poly(2-hydroxyethyl methacrylate) (poly(HEMA)) discs. Three groups of canine lens(More)
PURPOSE To determine matrix metalloproteinase (MMP) 2 and MMP 9 expression in acute and chronic experimentally wounded canine corneas and keratectomy samples from canine patients with spontaneous chronic corneal epithelial defects (SCCEDs). METHODS Mechanical debridement was performed unilaterally in 25 healthy dogs for the acute wound study. Twenty-four(More)
OBJECTIVE To assess the efficacy of a retrobulbar bupivacaine nerve block for postoperative analgesia following eye enucleation in dogs. DESIGN Randomized controlled trial. ANIMALS 22 dogs. PROCEDURES Client-owned dogs admitted to the hospital for routine eye enucleation were enrolled with owner consent and randomly assigned to a treatment(More)
OBJECTIVE Female dogs have approximately twice the risk of males for developing primary angle closure glaucoma (PACG). The cause of this gender difference is unknown, but one theory proposes that the gender differences in iridocorneal angle morphology are involved in this risk differential. PROCEDURES Fifty beagles (25 males, 25 females) were included(More)
CASE DESCRIPTION 6 dogs (10 eyes) with keratitis following long-term topical treatment with a carbonic anhydrase inhibitor (CAI) were evaluated. In 4 dogs (6 eyes), CAI treatment was discontinued. Three dogs (4 eyes) underwent enucleation because of end-stage corneal disease. One dog was treated differently in each eye and thus was represented in both(More)