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PURPOSE Treatment regimens for head and neck cancer patients profoundly affect several quality-of-life domains. Rehabilitative needs have been identified through cross-sectional analyses; however, few studies have prospectively assessed quality of life, included assessment of psychosocial variables, and identified predictors of long-term follow-up. (More)
The UCLA experience with juvenile angiofibroma (JNA) over a 25-year period is reviewed. There were 83 patients, the majority being adolescent males. Surgery was the primary method of treatment for disease not extending intracranially; 63 of 68 patients (92.5%) became asymptomatic with this modality. In patients treated with a single course of primary(More)
PURPOSE We have previously shown that a transcriptome is found in saliva and subpanels of these mRNAs can be used as oral cancer biomarkers. In this study, we measured the presence of microRNAs (miRNA) in saliva and determined their potential as an additional set of oral cancer biomarkers. EXPERIMENTAL DESIGN A total of 314 miRNAs were measured using(More)
OBJECTIVE To further understanding of treatment of papillary thyroid carcinoma (PTC). DESIGN The Surveillance, Epidemiology, and End Results Program database was searched for patients who had undergone surgery for PTC. SETTING Areas covered by Surveillance, Epidemiology, and End Results population-based registries. PATIENTS Patients who had undergone(More)
Cigarette smoking is a major risk factor for head and neck cancer, and individuals who continue to smoke past diagnosis and treatment are at elevated risk for further disease. In a randomized controlled trial, a state of the art provider-delivered smoking cessation intervention was compared to a usual care advice control condition. The intervention(More)
OBJECTIVE To determine the incidence and causes of perioperative complications in patients who undergo microvascular free flap procedures for reconstruction of the head and neck. SETTING Academic tertiary care medical center. PATIENTS AND METHODS A total of 400 consecutive microvascular free flap procedures were performed for reconstruction of the head(More)
Because of anatomical deformity, trismus, or for other reasons, it may on occasion be impossible to visualize a larynx by the usual laryngoscopy methods. Such difficulties in patients who have paralytic dysphonia may also make it impossible to effect improved vocal cord closure by the usual techniques of Teflon injection. We have applied a new technique,(More)
Rhinocerebral mucormycosis is recognized as a potentially aggressive and commonly fatal fungal infection. The classic presentation is involvement of nasal mucosa with invasion of the paranasal sinuses and orbit. Mucormycosis is most commonly seen in association with diabetic ketoacidosis, but disease demographics have changed with the onset of AIDS and the(More)
Magnetic resonance imaging (MRI)-guided fine needle aspiration was used to obtain tissue from lesions of the skull base for cytologic diagnoses in 14 patients. Our technique utilized a guiding system to enable three-dimensional orientation in a two-dimensional scan and a high nickel content 22 gauge needle to minimize significantly MRI artifact. Needle(More)
Evaluating the extent of tumor invasion of the mandible is clinically important in the management of mandibular tumors. Conventional imaging studies including panoramic radiography, bone scans, and computed tomography, as well as clinical evaluation can be unreliable in defining the extent of neoplastic marrow invasion. This study presents the initial UCLA,(More)