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BACKGROUND Pregnancy registries are a new method for assessing the fetal risks from exposures in pregnancy. We present the findings of the North American AED (antiepileptic drug) Pregnancy Registry for phenobarbital sodium-exposed pregnancies. OBJECTIVE To determine whether exposure during pregnancy to anticonvulsant drugs as monotherapy, and(More)
BACKGROUND Maternal atopic background and stimulation of the adaptive immune system with allergen interact in the development of allergic disease. Stimulation of the innate immune system through microbial exposure, such as activation of the innate Toll-like-receptor 2 (TLR2), may reduce the development of allergy in childhood. However, little is known about(More)
BACKGROUND The link between histologic acute chorioamnionitis and infection is well established in preterm deliveries, but less well-studied in term pregnancies, where infection is much less common. METHODOLOGY/PRINCIPAL FINDINGS We conducted a secondary analysis among 195 low-risk women with term pregnancies enrolled in a randomized trial. Histologic and(More)
BACKGROUND Delayed diagnosis of critical congenital heart disease (CCHD) in neonates increases morbidity and mortality. The use of pulse oximetry screening is recommended to increase detection of these conditions. The contribution of pulse oximetry in a tertiary-care birthing center may be different from at other sites. METHODS We analyzed CCHD pulse(More)
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