Ellen Hoffman

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Engineered zinc-finger nucleases (ZFNs) enable targeted genome modification. Here we describe context-dependent assembly (CoDA), a platform for engineering ZFNs using only standard cloning techniques or custom DNA synthesis. Using CoDA-generated ZFNs, we rapidly altered 20 genes in Danio rerio, Arabidopsis thaliana and Glycine max. The simplicity and(More)
The goal of integrating information technology into all facets of University life provides challenges to anticipate and provide for current and future computing needs of the entire University community. One response to the challenge is a concentrated effort to reach all students, from the computer anxious to the hacker. Since August, 1985, the Residence(More)
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