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Two Distinct Cyclodipeptide Synthases from a Marine Actinomycete Catalyze Biosynthesis of the Same Diketopiperazine Natural Product.

• Elle D James, Bryan Knuckley, +5 authors Amy L. Lane
• ACS synthetic biology
• 2016

Diketopiperazine natural products are structurally diverse and offer many biological activities. Cyclodipeptide synthases (CDPSs) were recently unveiled as a novel enzyme family that employs… (More)

Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis.

• Norah F. Alqahtani, Suheel Kumar Porwal, +4 authors Rajesh Viswanathan
• Organic & biomolecular chemistry
• 2015

Marine actinomycete-derived natural products continue to inspire chemical and biological investigations. Nocardioazines A and B (3 and 4), from Nocardiopsis sp. CMB-M0232, are structurally unique… (More)

Characterization of the nocardiopsin biosynthetic gene cluster reveals similarities to and differences from the rapamycin and FK-506 pathways.

• Dana M Bis, Yang H Ban, Elle D James, Norah F. Alqahtani, Rajesh Viswanathan, Amy L. Lane
• Chembiochem : a European journal of chemical…
• 2015

Macrolide-pipecolate natural products, such as rapamycin (1) and FK-506 (2), are renowned modulators of FK506-binding proteins (FKBPs). The nocardiopsins, from Nocardiopsis sp. CMB-M0232, are the… (More)

Correction: Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis.

• Norah F. Alqahtani, Suheel Kumar Porwal, +4 authors Rajesh Viswanathan
• Organic & biomolecular chemistry
• 2015

Correction for 'Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis' by Norah Alqahtani et al., Org. Biomol.… (More)

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