Elke Passos

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BACKGROUND AND OBJECTIVE To investigate the ocular toxicity of intravitreally administered tacrolimus, a drug with potent immunosuppressive activity. METHODS To evaluate toxicity, tacrolimus was injected into the midvitreous cavity of 20 eyes of New Zealand pigmented rabbits at concentrations of 10, 50, 100, 250, 500, and 1000 microg. Control eyes(More)
OBJECTIVE To investigate the use of the photosensitizer hypocrellin A as a photodynamic agent to occlude the choriocapillaris in the eyes of pigmented rabbits. METHODS Hypocrellin A (500 microg/kg) incorporated into liposomes was injected intravenously in pigmented rabbits. Ten to 15 minutes later, the retinas were irradiated with a dye laser (spot size,(More)
The aim of this study was to study the variation of isokinetic strength and bone mineral density on the lower limb in youth soccer players according to age level. Sixty-one youth male soccer players from three age groups (Under19, Under-17, and Under-15) take part on the study. Hamstrings and quadriceps concentric strength was evaluated by isokinetic(More)
To investigate the correlation between the length of external limiting membrane (ELM), ellipsoid zone (EZ) and interdigitation zone (IZ) defects and visual prognosis in patients undergoing macular hole (MH) surgery, using spectral-domain optical coherence tomography (SD-OCT). This is a retrospective, consecutive, observational case series study. Fifty-two(More)
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