Elke Isenberg

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BACKGROUND AND PURPOSE Endothelin peptides are potent vasoconstrictors and thus are seen as potential cause of cerebral vasospasm after subarachnoid hemorrhage (SAH). Earlier reports showed elevated or normal endothelin levels in plasma and cerebrospinal fluid in patients suffering from SAH. The present study was designed to determine whether endothelin is(More)
The pathogenetic relationship between tumour and hypertension was investigated in 129 patients with renal cell carcinoma, of whom 41 (31.8%) were hypertensive. Of these 41 patients with renal tumours and hypertension, 6 (14.6%) were found to have primary reninism. In these patients the plasma renin activity in blood from the renal veins showed a tumour(More)
Plasma big-endothelin (BE) in 12 patients with acute severe ischemic stroke was studied. Six patients developed complete supratentorial infarctions, and six patients had severe infarctions of pons, cerebellum, and/or medulla. Significant elevations of BE during the first 2 weeks after the initial stroke and significant differences between the(More)
Blood extent and localization visible in CCT predicts complications and prognosis in patients suffering from subarachnoid haemorrhage (SAH). Plasma renin activity (PRA) elevation is one of the hormonal parameters of autonomic disorders after SAH and its prognostic relevance could be confirmed by this study, too. But the correlation of PRA with blood amount(More)
Um Hinweise für eine mögliche pathologische Bedeutung niedriger Serumspiegel des Hormons Östradiol (E2) beim Mann zu gewinnen, wurde eine Normalbereichsbestimmung bei 91 gesunden Männern (Alter 20–75 Jahre) mit hohem und niedrigem Beschwerdeindex (klassifiziert nach testpsychologischem Fragebogen Beschwerdeliste B-L) vorgenommen. Die statistische(More)
Bei der Trigeminusneuralgie werden periphere und zentrale Entstehungsmechanismen diskutiert. Daher wurden bei 16 Patienten (53,3±8,3 Jahre) mit einer idiopathischen Trigeminusneuralgie in der Zerebrospinalflüssigkeit (CSF) die Neuropeptide Substanz P und Somatostatin, die Neurotransmitter Noradrenalin und Adrenalin sowie die Metaboliten(More)
Plasma big endothelin (BE) levels were studied in 17 patients during the first 2 weeks following spontaneous intracerebral hemorrhage (ICH). Three patients had experienced an infratentorial hemorrhage of the pons and cerebellum. The group of 14 patients with supratentorial hemorrhage presented with 8 hematomas of the putamen, 4 of the capsula interna and 2(More)
A simple and sensitive method for the determination of atropine in serum and protein solutions is presented. Atropine and procaine (internal standard) were extracted with diethylether from protein containing solutions after alkalinization. The residue of the evaporized ether phase, redissolved in diluted sulfuric acid, was injected directly onto a(More)