CD8 is a cell surface glycoprotein on major histocompatibility complex class I-restricted T cells. Thymocytes and most peripheral T cells express CD8 as heterodimers of CD8ot and CD8/3. The intestinal intraepithelial lymphocytes (IEL), which have been suggested to be generated extrathymically, express CD8 predominantly as homodimers of CD8ot. We have… (More)
Some format issues inherent in the e-media version may also appear in this print version.
This volume is a product of the staff of The World Bank. The findings, interpretations, and conclusions expressed in this volume do not necessarily reflect the views of the Executive Directors of The World Bank or the governments they represent. The World Bank does not guarantee the accuracy of the data included in this work. The boundaries, colors,… (More)
OBJECTIVE To study the effect of labyrinthectomy on the expression of NMDAR1 (N-methyl-D-aspartate receptor subunit R1). METHOD The in situ hybridization was used to observe the expression of NMDA R1mRNA post-unilateral labyrinthectomy and investigate its effect on vestibular compensation. RESULT 20 h post-unilateral labyrinthectomy, the NMDA R1mRNA… (More)
OBJECTIVE To further understand the traverse connections of nerve components in the vestibular sensory epithelium. METHODS The nerve innervations in the vestibular sensory epithelia and infraepithelia of ten healthy guinea pigs (16 ears) were observed by transmission electron microscopy. RESULTS Type I sensory cells were intricately connected with type… (More)
45CaCO3 was injected into guinea pigs, and the radioactivity in otolithic membranes of utriculi and sacculi, auditory ossicles and femora was determined by liquid scintillation spectrometry, to study the dynamic effect of streptomycin on calcium content of otolithic membranes, as a means to explore the mechanism of streptomycin ototoxicity. The results… (More)