Elizabeth Scholtz

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Many different formulation techniques are available for designing controlled-release dosage forms. Five different erosion-controlled or diffusion-controlled delivery systems were evaluated to select the 1 most suitable for Sinemet CR. The system ultimately selected, containing carbidopa-levodopa 50-200 mg, is a monolithic matrix tablet designed to have both(More)
Known since Biblical times (26) (36), but in local commercial cultivation only in the 20th Century, rooibos or red tea is now beginning to be exported from South Africa as a desirable, drugless addition to world beverages. Its appeal to the eye, nose, and taste, together with its soothing and reputedly health-giving properties, is receiving a welcome(More)
The point of zero charge of 36 carbonate-containing aluminum hydroxide gels decreased with increased carbonate-to-aluminum molar ratio. Theoretical analysis supported this observation and showed that the point of zero charge was sensitive to low fractional coverage of surface sites by carbonate and that divalent carbonate is the predominant form of(More)
In a prospective study 102 patients with malignant tumors of the tongue, oropharynx, hypopharynx, and larynx were staged by means of MRI. Special attention was directed at those tumour extensions that could influence the treatment strategy. The MR findings were correlated with the results of palpation, endoscopy, ultrasound, computerised tomography and(More)
Approximately 90% of the sodium present in a washed aluminum hydroxycarbonate gel was removed by exchange with magnesium. This behavior supports recent structural studies which have suggested that cations such as sodium serve as counterions in aluminum hydroxycarbonate gel. However, sodium could not be removed from dihydroxyaluminum sodium carbonate by(More)
Carbonate was completely desorbed from amorphous aluminum hydroxycarbonate gel by purging with nitrogen. The reversibility of carbonate adsorption suggests that aluminum hydroxycarbonate particles are composed of planes of aluminum hydroxide with carbonate adsorbed at edge aluminum sites. A slow-reacting phase which was identified as a precursor of(More)
Tramadol hydrochloride is a centrally acting opioid receptor agonist used for acute and chronic pain management in humans. Currently, tramadol is not labeled for use in veterinary species; however, it has been used with some success for the management of pain, particularly in cats and dogs. Previous studies conducted in horses have failed to achieve what is(More)