Elizabeth S. Parker

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This report describes AJ, a woman whose remembering dominates her life. Her memory is "nonstop, uncontrollable, and automatic." AJ spends an excessive amount of time recalling her personal past with considerable accuracy and reliability. If given a date, she can tell you what she was doing and what day of the week it fell on. She differs from other cases of(More)
In two experiments with normal male subjects, the ingestion of alcohol (1 ml/kg) immediately after learning significantly improved subsequent remembering. By comparison, marijuana (15 mg) had no significant post-acquisition effect. Facilitation of visual and verbal memory with alcohol under these conditions has implications for the interference and(More)
Research on alcohol amnesia has focused on memory processes that are disrupted during intoxication. The present experiment examined the possibility that certain memory processes might be resistant to the amnesic effects of alcohol. Intoxicated and sober subjects studied a list of 29 words. They were then given one of three different retention tests: free(More)
Little is known about acute effects of alcohol on memory encoding and retrieval on different limbs (ascending and descending) of the blood alcohol concentration (BAC) curve. This extensive experiment was designed to examine alcohol's effects on memory encoding and retrieval throughout a protracted drinking episode. In a 9-h session, male participants(More)
Sixteen normal male subjects participated in four sessions where they studied a set of pictures followed by either placebo, 0.025, 0.50, or 1.0 ml/kg alcohol. Later, when sober, recognition memory was tested. These doses resulted in peak blood alcohol concentrations (BAC) of 0.00, 0.018, 0.034, and 0.067 g/100 ml, respectively. The 1.0 and 0.50 ml/kg doses(More)
OBJECTIVE To determine the nature and extent of cognitive deficits in early stage (asymptomatic) human immunodeficiency virus (HIV)-positive homosexual and bisexual men. DESIGN A cross-sectional design was used to compare 27 HIV-positive, asymptomatic (Centers for Disease Control and Prevention stages 2 and 3) homosexual and bisexual men, who were(More)
Immediate post-training IP injection of ethanol (0.75–4.5 g/kg) significantly enhanced retention of a one-trial passive avoidance task in mice compared to saline controls. Ethanol (4.5 g/kg) in the absence of footshock did not affect test performance. The memory facilitation may reflect ethanol's effects on neurotransmitter, macromolecular, or hormonal(More)
The effects of alcohol on formal aspects of social communication were studied by scoring transcripts of verbal discussions between dyads in alcohol and placebo sessions. At a low dose (3.83 to 1.0 ml/kg), alcohol significantly (P Less than .01) increased the amount of and overlap in communications, and tended to decrease subjects' acknowledgement of their(More)
Exposure to 12 atmospheres absolute (12 ATA) helium oxygen gas (heliox) (low level hyperbaric exposure) antagonizes the behavioral effects of ethanol and n-propanol, but not morphine. These and other results indicate that the mechanism of the antagonism is direct (pharmacodynamic) and selective. Our study further investigates the selectivity of low level(More)
Amnestic mild cognitive impairment (MCI) is a selective episodic memory deficit that often indicates early Alzheimer's disease. Episodic memory function in MCI is typically defined by deficits in free recall, but can also be tested using recognition procedures. To assess both recall and recognition in MCI, MCI (n = 21) and older comparison (n = 30) groups(More)