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- Publications
- Influence
The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells
- B. Plitzko, E. N. Kaweesa, S. Loesgen
- Biology, Medicine
- The Journal of Biological Chemistry
- 26 October 2017
Mensacarcin is a highly oxygenated polyketide that was first isolated from soil-dwelling Streptomyces bacteria. It exhibits potent cytostatic properties (mean of 50% growth inhibition = 0.2 μm) in… Expand
Coculture of Two Developmental Stages of a Marine-Derived Aspergillus alliaceus Results in the Production of the Cytotoxic Bianthrone Allianthrone A.
- P. E. Mandelare, D. Adpressa, E. N. Kaweesa, L. Zakharov, S. Loesgen
- Chemistry, Medicine
- Journal of natural products
- 8 March 2018
The genetically encoded, small-molecule chemical diversity of filamentous fungi is still largely unexplored and represents an attractive source for the discovery of new compounds. Here we report the… Expand
Bioenergetics underlying single cell migration on aligned nanofiber scaffolds.
- A. Padhi, Alexander H Thomson, +7 authors D. Brown
- Chemistry, Medicine
- American journal of physiology. Cell physiology
- 25 December 2019
Cell migration is centrally involved in a myriad of physiological processes, including morphogenesis, wound healing, tissue repair, and metastatic growth. The bioenergetics that underlie migratory… Expand
Chemical, Bioactivity, and Biosynthetic Screening of Epiphytic Fungus Zasmidium pseudotsugae
- Gisela A González-Montiel, E. N. Kaweesa, N. Feau, R. Hamelin, J. K. Stone, S. Loesgen
- Chemistry, Medicine
- Molecules
- 1 May 2020
We report the first secondary metabolite, 8,8′-bijuglone, obtained from pure cultures of the slow growing Douglas fir- (Pseudotsuga menziesii var. menziesii) foliage-associated fungus Zasmidium… Expand