Elizabeth M. Smith

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Fluorescence studies of cellular protein-protein interactions commonly employ transient cotransfection to express two proteins carrying distinct fluorescent labels. Because transiently transfected cells differ significantly in their expression level, the concentration ratio of the two expressed proteins varies, which in turn influences the measured(More)
Much of the mechanistic details for how HTLV-1 Gag orchestrates virus particle assembly and release are poorly understood. Here, we monitored the behavior of both membrane-bound and cytoplasmic HTLV-1 Gag in real-time in living cells incubated on a fluorescence microscope. We used both fluorescence fluctuation spectroscopy (FFS, conventional and z-scan) and(More)
Integrin Receptor Antagonist 5 β v α and 3 β v α a Dual ABSTRACT New blood vessel formation is essential for tumor growth and meta-static spread. Integrins ␣ v ␤ 3 and ␣ v ␤ 5 are arginine-glycine-aspartic acid-dependent adhesion receptors that play a critical role in angiogenesis.
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