Elizabeth L. Gibson

Learn More
In a descriptive experiment on discrimination five human subjects were studied during the transitional period of sleep onset. Subjects were aroused by an abrupt auditory stimulus, attempted to discriminate the pre-arousal stage by a behavioral response, and answered a series of standardized questions. These questions focused on specific characteristics of(More)
CALHM1 is a cell surface calcium channel expressed in cerebral neurons. CALHM1 function in the brain remains unknown, but recent results showed that neuronal CALHM1 controls intracellular calcium signaling and cell excitability, two mechanisms required for synaptic function. Here, we describe the generation of Calhm1 knockout (Calhm1(-/-)) mice and(More)
Patients with chronic kidney disease (CKD) often require regular hemodialysis (HD) to prolong life. However, between HD sessions, patients have to restrict their diets carefully to avoid excess accumulation of potassium, phosphate, sodium, and fluid, which their diseased kidneys can no longer regulate. Failure to adhere to their renal dietary regimes can be(More)
We present a succinct review of our approach to study the interactions between the DNA-reactive antibodies that cross-react with the GluN2A and GluN2B subunits of the N-methyl-D-aspartate receptor, denoted DNRABs, and their brain targets in subjects with neuropsychiatric systemic lupus erythematosus (NPSLE). We have analyzed the DNRAB-based brain(More)
Six subjects participated in a one-night sleep-onset experiment. They were aroused from stage 1 and stage 2 as defined by standard electroencephalographic criteria. Subjects pressed a button upon arousal to indicate which of two subjective states they were in just before awakening. Performance accuracy from stage 1 awakenings appeared to remain relatively(More)
  • 1