Elizabeth K Storer

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Synaptic efficacy requires that presynaptic and postsynaptic specializations align precisely and mature coordinately. The underlying mechanisms are poorly understood, however. We propose that adenomatous polyposis coli protein (APC) is a key coordinator of presynaptic and postsynaptic maturation. APC organizes a multiprotein complex that directs nicotinic(More)
Muscular dystrophy patients often show cognitive impairment, in addition to muscle degeneration caused by dystrophin gene defects. The cognitive impairments lead to speculation that the dystrophin protein family may play a key role at neuronal synapses. Dystrophin regulates the stability of selected GABA(A) receptor subtypes and alpha3-containing nicotinic(More)
Major Overview: The Molecular Environmental Biology (MEB) major is designed to train students in the organization and function of biological organisms and their integration into the environment. MEB graduates acquire a broad foundation across a breadth of biological core areas, which gives them especially valuable scientific training. The MEB degree(More)
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