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PURPOSE We undertook this study to determine the activity and tolerability of sorafenib administered with interferon alfa-2b (IFN-alpha-2b) as first- or second-line therapy in metastatic renal cell cancer (RCC). PATIENTS AND METHODS Between November 2004 and October 2006, 40 patients at two sites were enrolled onto a phase II trial of sorafenib plus(More)
The present study evaluated and compared the psychometric properties of three self-report scales: the Snaith-Hamilton Pleasure Scale (SHAPS; R. P. Snaith, M. Hamilton, S. Morley, & A. Humayan, 1995), Fawcett-Clark Pleasure Capacity Scale (FCPS; J. Fawcett, D. C. Clark, W. A. Scheftner, & R. D. Gibbons, 1983), and the Revised Chapman Physical Anhedonia Scale(More)
OBJECTIVE The objective of this study was to examine the relationship of primary caregivers' literacy with children's oral health outcomes. METHODS We performed a cross-sectional study of children who were aged < or =6 years and presented for an initial dental appointment in the teaching clinics at the University of North Carolina at Chapel Hill School of(More)
Early loss of immature permanent teeth due to pulpal necrosis secondary to trauma can have dire consequences for a child's growth and development. The treatment alternatives include surgical endodontics, traditional calcium hydroxide apexification, and mineral trioxide aggregate (MTA) apexification. These options pose potential complications, including:(More)
Cognitive processing biases toward smoking-related and affective cues may play a role in tobacco dependence. Because processing biases may occur outside conscious awareness, the current study examined processing of smoking-related and affective stimuli presented at subliminal conditions. A pictorial subliminal repetition priming task was administered to(More)
This paper expands upon the recent report of the expert panel commissioned by the American Dental Association's Council on Scientific Affairs by offering evidence-based clinical recommendations for professionally applied topical fluoride. The authors strongly support the panel's recommendation that clinicians should rely upon caries risk criteria for(More)
The Implicit Association Test (IAT) is widely used to assess automatic associations in memory. The feasibility of administering the test in an Ecological Momentary Assessment setting was examined with 15 smokers and 15 nonsmokers who carried a handheld computer for 1 wk. as they went about their daily lives. They completed the Implicit Association Test on(More)
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