The use of antiretroviral therapy as post-exposure prophylaxis against human immunodeficiency virus (HIV) is now routine following high-risk exposure to the HIV virus. This article summarizes the management of health care workers and others exposed to HIV in an occupational setting, and the evidence behind it.
OBJECTIVES The magnitude of HIV viral rebound following ART cessation has consequences for clinical outcome and onward transmission. We compared plasma viral load (pVL) rebound after stopping ART initiated in primary (PHI) and chronic HIV infection (CHI). DESIGN Two populations with protocol-indicated ART cessation from SPARTAC (PHI, n = 182) and SMART… (More)
Treatment of HIV-1 infection with antiretroviral therapy (ART) in the weeks following transmission may induce a state of 'post-treatment control' (PTC) in some patients, in whom viraemia remains undetectable when ART is stopped. Explaining PTC could help our understanding of the processes that maintain viral persistence. Here we show that immunological… (More)
Dr. Burton has asked how to screen a patient for allergy in the absence of a reliable test. The steps for allergy screening are as follows: 1. Search for a family history of allergy. When there are allergies on both sides of the family an allergic diathesis is very likely. 2. As a new born baby was the patient easy to rear or did it cry excessively, have… (More)