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In adults, primary malignant brain tumors (PMBT) are rare, but they have a devastating impact and the chances for survival are limited. UK clinical guidance on supportive care for patients with brain and central nervous system tumors was published in 2006 and relied on very limited evidence. The current article reviews literature from 2005 through 2011 on(More)
Lying and deception are behaviors that have been studied and discussed extensively in the scientific, philosophical and legal communities for centuries. The purpose of this article is to provide a general overview of the literature and thinking to date about deception, followed by an analysis of the efficacy and evolution of lie detection techniques. The(More)
BACKGROUND There is converging evidence that approximately 2% of women fulfill PTSD criteria following childbirth. This study examined the presentation and symptom structure of PTSD after birth and key risk factors in women from internet and community samples. METHODS PTSD was measured in 1423 women after birth recruited via the community (n=502) or(More)
A literature review confirms a need for improved medical education on death, dying, terminal illness, and bereavement, and so palliative care, from 1900 until the present time in the UK, Australia, New Zealand, USA, and Canada. The origins of the hospice movement and its influence are also discussed. Current palliative care teaching is recorded in a table(More)
INTRODUCTION Cigarette smoking may induce pro-inflammatory and pro-thrombotic changes. It is not known whether these abnormalities are caused at least partly by increased homocysteine levels. We investigated whether lowering homocysteine by folic acid supplementation might reduce the plasma concentration of inflammatory and thrombogenic markers in chronic(More)
UNLABELLED Women can suffer from post-traumatic stress disorder (PTSD) following childbirth. This study investigated the application of a cognitive model to PTS symptoms following childbirth and explored the addition of social support to the model. METHODS Women (N=138) completed questionnaires in pregnancy, 3-weeks and 3-months after birth, measuring(More)
BACKGROUND Research using electronic health records (EHRs) relies heavily on coded clinical data. Due to variation in coding practices, it can be difficult to aggregate the codes for a condition in order to define cases. This paper describes a methodology to develop 'indicator markers' found in patients with early rheumatoid arthritis (RA); these are a(More)
BACKGROUND Primary care databases are a major source of data for epidemiological and health services research. However, most studies are based on coded information, ignoring information stored in free text. Using the early presentation of rheumatoid arthritis (RA) as an exemplar, our objective was to estimate the extent of data hidden within free text,(More)
After a single feeding or intravenous injection of 7,12-dimethylbenz[a]anthracene, the testis of rat was severely and selectively damaged, whereas the ovary of sisters was spared from injury. After many weeks, complete recovery of the testis ensued. The destructive effect of 7,12-DMBA on testis was not shared by other powerful carcinogenic hydrocarbons;(More)
UNLABELLED Following childbirth, 16% of women may have anxiety disorders and 2% develop PTSD. It is important to identify factors that influence women's emotional reactions to birth. This study investigated how stressful events and support from hospital staff during birth each affects women's anxiety and perceived control. METHODS A between-subjects(More)