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Cytochrome P450 (CYP) 2E1 is implicated in a variety of chemically initiated hepatotoxicities, including alcoholic liver disease. These pathological conditions arise from increased production of reactive intermediates caused by elevated enzyme concentrations. Thus, the ability to detect enhanced CYP2E1 levels would aid in identifying individuals at high… (More)
We examined the potential for the widely consumed xenobiotic ethanol to transplacentally induce fetal rat CYP2E1. Throughout gestation, rat dams were fed a liquid diet containing 5% ethanol or two separate control diets. At 2 days before term, the dams were killed, and maternal and embryonic tissues were collected. Immunoblot analysis of microsomes from… (More)
Schultz, Emily, "Antecedentes del movimiento actual para la independencia de Cataluña: Una aproximación multidisciplinaria" (2015).
Grating acuity was tested in 74 subjects with different amblyopia and five patients with pathological morphological findings, reducing visual acuity. Recognition acuity was tested with Landolt C single symbol and close inter-space 2.6 min. of arc. Grating acuity was tested with the Teller Acuity Cards with large (12.5 cm × 12.5 cm) and small (6.25 cm × 6.25… (More)
Executive Summary 8 The Whole of Government Approach 10 Ambiguity surrounding the " whole of government " approach 11 Departmental preference for different types of coordination 12 Insecure environments put strain on coordination mechanisms 13 Strategies to achieve successful coordination 14 Objectives, Timelines, & Transitions 16 Different objectives… (More)