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- Joel E. Schlosburg, Jacqueline L. Blankman, +13 authors Benjamin F Cravatt
- Nature Neuroscience
- 2010
Prolonged exposure to drugs of abuse, such as cannabinoids and opioids, leads to pharmacological tolerance and receptor desensitization in the nervous system. We found that a similar form of… (More)
- Elizabeth Anne Thomas, Giovanni Coppola, +9 authors Joel M. Gottesfeld
- Proceedings of the National Academy of Sciences…
- 2008
Transcriptional dysregulation has emerged as a core pathologic feature of Huntington's disease (HD), one of several triplet-repeat disorders characterized by movement deficits and cognitive… (More)
- Sherman Ku, Elisabetta Soragni, +6 authors Joel M. Gottesfeld
- Cell stem cell
- 2010
The inherited neurodegenerative disease Friedreich's ataxia (FRDA) is caused by GAA⋅TTC triplet repeat hyperexpansions within the first intron of the FXN gene, encoding the mitochondrial protein… (More)
- Sujatha Narayan, Bin Tang, +4 authors Elizabeth Anne Thomas
- Brain Research
- 2008
Results from clinical and imaging studies provide evidence for changes in schizophrenia with disease progression, however, the underlying molecular differences that may occur at different stages of… (More)
- Katharine Trenholme, Donald L. Gardiner, Deborah C. Holt, Elizabeth Anne Thomas, Alan F Cowman, David J. Kemp
- Proceedings of the National Academy of Sciences…
- 2000
The propensity of isolates of the malaria parasite Plasmodium falciparum to delete a segment of chromosome 9 has provided positional information that has allowed us to identify a gene necessary for… (More)
- Liliana Losada, Suman B. Pakala, +11 authors Marc A. Cubeta
- FEMS microbiology letters
- 2014
The soil fungus Rhizoctonia solani is an economically important pathogen of agricultural and forestry crops. Here, we present the complete sequence and analysis of the mitochondrial genome of R.… (More)
- Elizabeth Anne Thomas, Monica J. Carson, Michael J. Neal, J. Gregor Sutcliffe
- Proceedings of the National Academy of Sciences…
- 1997
The effects of oleamide, an amidated lipid isolated from the cerebrospinal fluid of sleep-deprived cats, on serotonin receptor-mediated responses were investigated in cultured mammalian cells. In rat… (More)
- Bin Tang, Wei-Li Chang, Caroline M. S. Lanigan, Brian Dean, J. Gregor Sutcliffe, Elizabeth Anne Thomas
- Aging cell
- 2009
We examined genome-wide expression datasets from human prefrontal cortex of normal and schizophrenic individuals ranging from 19 to 81 years of age. We found that changes in gene expression that are… (More)
- Elizabeth Anne Thomas, Brian Dean, Geoffrey M Pavey, J. Gregor Sutcliffe
- Proceedings of the National Academy of Sciences…
- 2001
Chronic administration of the atypical antipsychotic drug, clozapine, to rodents has been shown to increase the concentration of apolipoprotein D (apoD) in several area of the brain, suggesting that… (More)
- Elizabeth Anne Thomas, Benjamin F Cravatt, Patria E. Danielson, Norton B. Gilula, J. Gregor Sutcliffe
- Journal of neuroscience research
- 1997
Fatty acid amide hydrolase (FAAH) is a membrane-bound enzyme activity that degrades neuromodulatory fatty acid amides, including oleamide and anandamide. A single 2.5-kb FAAH mRNA is distributed… (More)