Elise de la Rochebrochard

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BACKGROUND It is well known that miscarriage risk increases with age. However, studies usually investigate only maternal age effects. We investigated both maternal age and paternal age effects on miscarriage risk to provide insight into this frequent reproductive failure. METHODS The last planned pregnancies (n = 3174) that ended in a birth or miscarriage(More)
OBJECTIVE To investigate paternal age effect mediated by biological modifications with use of data from assisted reproductive technologies. DESIGN National IVF registry. SETTING Fifty nine French IVF centers. PATIENT(S) A total of 1,938 men whose partners were totally sterile, with bilateral tubal obstruction or absence of both tubes (to avoid bias(More)
OBJECTIVE To determine the frequency of live births following spontaneous pregnancy (BSP) and to examine their associated factors among couples who have unsuccessfully or successfully experienced fertility treatments. DESIGN Retrospective cohort. SETTING Eight IVF centers. PATIENT(S) A total of 2,134 couples who began IVF treatment in the centers in(More)
BACKGROUND Reports of a secular decrease in semen quality remain controversial, particularly due to the possibility of selection bias. We aimed to describe the potential bias due to self-selection of volunteers in semen studies involving fecund men. METHODS Using data from the French multicentre study REPRHOM, we compared the characteristics of the(More)
BACKGROUND The Ages and Stages Questionnaire (ASQ), completed by parents and caregivers, has been shown to be an accurate tool for screening children who need further developmental assessment. AIMS To assess the feasibility of using the French Canadian translation of the ASQ in an epidemiological cohort of children from the French general population. (More)
BACKGROUND The outcome of in vitro fertilization (IVF) has been widely investigated over the last 30 years, but evaluation was mostly based on pregnancy rate per oocyte retrieval. Our objective was to estimate the cumulative live birth rate after four IVF aspirations, using multiple imputation that takes into account treatment interruptions. METHODS We(More)
OBJECTIVE The purpose of this study was to examine the risk of infertility that is associated with paternal age, because this factor rarely has been investigated, whereas maternal age of >or=35 years is a well-known risk factor. STUDY DESIGN This large, retrospective, population-based sample included 6188 European women (from Denmark, Italy, Spain,(More)
BACKGROUND In longitudinal cohort studies, subjects may be lost to follow-up at any time during the study. This leads to attrition and thus to a risk of inaccurate and biased estimations. The purpose of this paper is to show how multiple imputation can take advantage of all the information collected during follow-up in order to estimate the cumulative(More)
Our goals were to (1) validate the parental Ages and Stages Questionnaires (ASQ) as a screening tool for psychomotor development among a cohort of ex-premature infants reaching 2 years, and (2) analyse the influence of parental socio-economic status and maternal education on the efficacy of the questionnaire. A regional population of 703 very preterm(More)
BACKGROUND Maternal age of 35 years or over is a well-known risk factor for human reproduction that has been extensively investigated by demographers and epidemiologists. However, the possibility of a paternal age effect has rarely been considered. We carried out review of the literature to investigate the effect of paternal age on the risks of infecundity(More)