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- Dianna L. Bartel, Susan Laura Sullivan, Elise G. Lavoie, Jean Sévigny, Thomas E Finger
- The Journal of comparative neurology
- 2006
The presence of one or more calcium-dependent ecto-ATPases (enzymes that hydrolyze extracellular 5'-triphosphates) in mammalian taste buds was first shown histochemically. Recent studies have… (More)
- Sebastien Levesque, Elise G. Lavoie, Joanna Lecka, François Bigonnesse, Jean Sévigny
- British journal of pharmacology
- 2007
BACKGROUND AND PURPOSE
ARL 67156, 6-N,N-Diethyl-D-beta-gamma-dibromomethylene adenosine triphosphate, originally named FPL 67156, is the only commercially available inhibitor of ecto-ATPases. Since… (More)
- Elise G. Lavoie, Michel Fausther, +4 authors Jean Sévigny
- American journal of physiology. Endocrinology and…
- 2010
Extracellular nucleotides and adenosine regulate endocrine pancreatic functions such as insulin secretion by Langerhans islet β-cells via the activation of specific P2 and P1 receptors.… (More)
- Elise G. Lavoie, Filip Kukulski, Sebastien Levesque, Joanna Lecka, Jean Sévigny
- Biochemical pharmacology
- 2004
We have cloned and characterized the nucleoside triphosphate diphosphohydrolase-3 (NTPDase3) from mouse spleen. Analysis of cDNA shows an open reading frame of 1587 base pairs encoding a protein of… (More)
- Muhammad Nauman Jhandier, Emma A. Kruglov, Elise G. Lavoie, Jean Sévigny, Jonathan A. Dranoff
- The Journal of biological chemistry
- 2005
Bile duct epithelia are the target of a number of "cholangiopathies" characterized by disordered bile ductular proliferation. Although mechanisms for bile ductular proliferation are unknown, recent… (More)
- Elise G. Lavoie, Brian D Gulbransen, Mireia Martín-Satué, Elisabet Aliagas, Keith A Sharkey, Jean Sévigny
- American journal of physiology. Gastrointestinal…
- 2011
Extracellular nucleotides and adenosine are biologically active molecules that bind members of the P2 and P1 receptor families, respectively. In the digestive system, these receptors modulate various… (More)
- Mercedes Nancy Munkonda, Gilles Kauffenstein, +6 authors Jean Sévigny
- Biochemical pharmacology
- 2007
The plasma membrane bound nucleoside triphosphate diphosphohydrolase (NTPDase)-1, 2, 3 and 8 are major ectonucleotidases that modulate P2 receptor signaling by controlling nucleotides' concentrations… (More)
- Jin Yu, Elise G. Lavoie, Nina Sheung, Jacques J. Tremblay, Jean Sévigny, Jonathan A. Dranoff
- American journal of physiology. Gastrointestinal…
- 2008
Bile ductular proliferation is markedly upregulated in biliary fibrosis and cirrhosis. However, the mechanisms regulating this upregulation in bile ductular proliferation have not been defined.… (More)
Ectonucleoside triphosphate diphosphohydrolases (E-NTPDases) are a family of membrane-bound enzymes that hydrolyze extracellular di- and triphosphate nucleosides. E-NTPDases have been proposed to… (More)
- Gilles Kauffenstein, Julie Pelletier, +11 authors Jean Sévigny
- The Journal of biological chemistry
- 2014
In this work, we report that Entpd1(-/-) mice, deficient for the ectonucleotidase nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), produce smaller litters (27% reduction) compared with… (More)