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This project aims to assess the utility of bibliographic databases beyond the three major ones (MEDLINE, EMBASE and Cochrane CENTRAL) for finding controlled trials of complementary and alternative medicine (CAM). Fifteen databases were searched to identify controlled clinical trials (CCTs) of CAM not also indexed in MEDLINE. Searches were conducted in May(More)
BACKGROUND Explicit patient consent requirements in privacy laws can have a negative impact on health research, leading to selection bias and reduced recruitment. Often legislative requirements to obtain consent are waived if the information collected or disclosed is de-identified. OBJECTIVE The authors developed and empirically evaluated a new globally(More)
BACKGROUND A knowledge synthesis attempts to summarize all pertinent studies on a specific question, can improve the understanding of inconsistencies in diverse evidence, and can identify gaps in research evidence to define future research agendas. Knowledge synthesis activities in healthcare have largely focused on systematic reviews of interventions.(More)
OBJECTIVE To summarize the evidence concerning bias and confounding in conducting systematic reviews (SRs). STUDY DESIGN AND SETTING Literature was identified through searching the Cochrane Library, MEDLINE, PsycINFO until November 2006, and the authors' files. Studies were included if they were SRs of bias that can occur while conducting a SR. Risk of(More)
INTRODUCTION Knowledge translation (KT also known as research utilisation, translational medicine and implementation science) is a dynamic and iterative process that includes the synthesis, dissemination, exchange and ethically sound application of knowledge to improve health. After the implementation of KT interventions, their impact on relevant outcomes(More)
BACKGROUND Numerous, often multi-faceted regimens are available for treating complex wounds, yet the evidence of these interventions is recondite across the literature. We aimed to identify effective interventions to treat complex wounds through an overview of systematic reviews. METHODS MEDLINE (OVID interface, 1946 until October 26, 2012), EMBASE (OVID(More)
BACKGROUND Epilepsy affects about 1% of the general population. Anti-epileptic drugs (AEDs) prevent or terminate seizures in individuals with epilepsy. Pregnant women with epilepsy may continue taking AEDs. Many of these agents cross the placenta and increase the risk of major congenital malformations, early cognitive and developmental delays, and infant(More)
OBJECTIVE To explore and categorise the state of existing literature for national programmes designed to affirm or establish the continuing competence of physicians. DESIGN Scoping review. DATA SOURCES MEDLINE, ERIC, Sociological Abstracts, web/grey literature (2000-2014). SELECTION Included when a record described a (1) national-level physician(More)
BACKGROUND Knowledge translation (KT, also known as research utilization, and sometimes referring to implementation science) is a dynamic and iterative process that includes the synthesis, dissemination, exchange, and ethically sound application of knowledge to improve health. A KT intervention is one which facilitates the uptake of research. The long-term(More)