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International Union of Basic and Clinical Pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors.
The activation of the complement cascade, a cornerstone of the innate immune response, produces a number of small (74-77 amino acid) fragments, originally termed anaphylatoxins, that are potent… Expand
International Union of Basic and Clinical Pharmacology. LXXXVII. Complement Peptide C5a, C4a, and C3a Receptors
The activation of the complement cascade, a cornerstone of the innate immune response, produces a number of small (74–77 amino acid) fragments, originally termed anaphylatoxins, that are potent… Expand
Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate‐induced models of inflammatory bowel disease
- Kay O. Johswich, M. Martín, +7 authors Andreas Klos
- Inflammatory bowel diseases
- 1 December 2009
Background: Inflammatory bowel disease (IBD) is a critical public health issue; more and more people are affected, but treatment options remain limited. Complement activation and the anaphylatoxin… Expand
MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation
BackgroundMelanoma cells are usually characterized by a strong proliferative potential and efficient invasive migration. Among the multiple molecular changes that are recorded during progression of… Expand
The Complement Anaphylatoxin C3a Receptor (C3aR) Contributes to the Inflammatory Response in Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice
Inflammatory bowel diseases are a critical public health issue, and as treatment options remain limited, there is a need to unravel the underlying pathomechanisms in order to identify new therapeutic… Expand
The oncogenic epidermal growth factor receptor variant Xiphophorus melanoma receptor kinase induces motility in melanocytes by modulation of focal adhesions.
- S. Meierjohann, Elisabeth Wende, A. Kraiss, C. Wellbrock, M. Schartl
- Biology, Medicine
- Cancer research
- 15 March 2006
One of the most prominent features of malignant melanoma is the fast generation of metastasizing cells, resulting in the poor prognosis of patients with this tumor type. For this process, cells must… Expand
Candida albicans’ pH regulated antigen 1 (Pra1) preferentially targets and inactivates human complement C3 and C3 activation fragments to evade host immune attack
Amoeboid migration in transformed melanocytes