Elisabeth Macintyre

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The incidence of follicular lymphoma (FL) in industrialized countries has been increasing since the 1950s. Polymorphisms in genes encoding key enzymes controlling folate-methionine metabolism, including methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MS or MTR), serine hydroxymethyltransferase (SHMT), and thymidylate synthase (TS or TYMS),(More)
Base layers of untransformed normal embryonic lung fibroblasts in different stages of growth were challenged with RSV (Rous sarcoma virus)-transformed bovine fibroblasts. The effect of this admixture on the growth of the RSV-transformed cells was studied. In all cases, the transformed cells proliferated freely, and it is concluded that the normal cells(More)
Comparison of human astrocytes (1181N1 line) and sheep choroid plexus cells (SCP) infected with visna virus (V-1181N1 and V-SCP) shows that the mode of virus assembly and the morphology and size of the free virions are identical in the 2 systems. V-SCP cells usually cytolyse soon after infection; V-1181N1 cells do not. This is considered to be due to(More)