Elisabet Coll

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Cystatin C is a nonglycosylated basic protein produced at a constant rate by all investigated nucleated cells. It is freely filtered by the renal glomeruli and primarily catabolized in the tubuli (not secreted or reabsorbed as an intact molecule). Because serum cystatin C concentration is independent of age, sex, and muscle mass, it has been postulated to(More)
Chronic hypotension, defined by a systolic blood pressure < 100 mmHg in the interdialytic period, affects 5-10% of hemodialysis patients, and is more prevalent among patients on long-term hemodialysis. This complication requires a substantial amount of medical and nursing care before and during dialysis to control its symptoms. Chronic hypotension is(More)
Key words: orofacial syndrome type I; X-linked domin-were poorly formed and badly placed. At 7 years of ant disease; polycystic kidneys; renal replacement age she was unable to speak correctly because of therapy dysarthria. She had also diÃculty on moving (lack of balance, lack of accuracy). At 14 years of age she had a spinal fusion because of(More)
UNLABELLED Intradialytic hypotension is closely linked to hypovolemia and ascribed to the degree of ultrafiltration. Among the maneuvers used to recovery hypotension, we have the Trendelenburg position, the infusion of isotonic saline serum or plasma extenders as well as shutting of the ultrafiltration. The objective of this study is to quantify the(More)
BACKGROUND Chronic renal failure (CRF) patients present a high incidence of cardiovascular pathologies and cancer. This has been attributed to the existence of genomic instability in these patients, and consequently they should present elevated levels of genetic damage. METHODS To determine the background levels of genetic damage and its specific levels(More)
SUMMARY BACKGROUND The small quantity of acetate present in the dialysis fluid exposes patient's blood to an acetate concentration 30-40 times the physiological levels. This amount is even greater in hemodiafiltration on-line. Our purpose was to evaluate the clinical-analytical effects using three different dialysis techniques in the same patient. METHODS(More)
It is assumed that hemodialysis treatment can diminish the levels of genetic damage in circulating lymphocytes by cleaning the blood of uremic toxins that cause oxidative stress. However, the hemodialysis process by itself may also induce genomic damage by producing reactive oxygen species (ROS). We conducted a follow-up study in a group of 70 hemodialysis(More)
Chronic kidney disease (CKD) patients are characterized by elevated levels of genomic damage. This damage increases when kidney function decreases being maximum in hemodialysis patients. As kidney transplantation improves renal function, and it is related with better survival, the aim of our study was to evaluate potential changes in DNA damage levels after(More)
PURPOSE Patients suffering from chronic kidney disease (CKD) exhibit a high incidence of cancer, as well as high levels of genetic damage. We hypothesized that these patients show genomic instability detected as an increased chromosomal radiosensitivity in front of the genetic damage induced by ionizing radiation. MATERIAL AND METHODS The background(More)