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Inflammatory bowel diseases are chronic gastrointestinal pathologies causing great discomfort in both children and adults. The pathogenesis of inflammatory bowel diseases is not yet fully understood and their diagnosis and treatment are often challenging. Nanoparticle-based strategies have been tested in local drug delivery to the inflamed colon. Here, we(More)
Chronic gastro-duodenal reflux in the esophagus is a major risk for intestinal metaplasia and Barrett's adenocarcinoma. A role for chronic use of proton pump inhibitor (PPI) in the increased incidence of esophageal adenocarcinoma in Western countries has been previously suggested. The aim of this work was to study the effect of chronic administration of(More)
Discussions This discussion paper is/has been under review for the journal Climate of the Past (CP). Please refer to the corresponding final paper in CP if available. Abstract The influence of salinity in the incorporation of trace elements in the skeleton of cal-careous organisms is still poorly known. Studies on foraminiferal Mg / Ca thermometry have(More)
PURPOSE While adherence to the World Cancer Research Fund (WCRF) guidelines on lifestyle and cancer was recently proven to be associated with an increased risk of esophageal cancer, no investigation has yet been carried out on its role on Barrett's esophagus (BE) development and its progression to esophageal adenocarcinoma (EAC). The primary aim of this(More)
For many years, novel strategies for cancer detection and treatment using nanoparticles (NPs) have been developed. Esophageal adenocarcinoma is the sixth leading cause of cancer-related deaths in Western countries, and despite recent advances in early detection and treatment, its prognosis is still very poor. This study investigated the use of fluorescent(More)
Porites coral-based sea surface temperature (SST) reconstructions are obtained from the measurement of skeleton Sr / Ca ratio. However, the influence of salinity in the incorporation of these trace elements in the Porites aragonitic skeleton is still poorly documented. Laboratory experiments indicate that in three different coral species (not including the(More)
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