Elisa Cesarini

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The basic unit of genome packaging is the nucleosome, and nucleosomes have long been proposed to restrict DNA accessibility both to damage and to transcription. Nucleosome number in cells was considered fixed, but recently aging yeast and mammalian cells were shown to contain fewer nucleosomes. We show here that mammalian cells lacking High Mobility Group(More)
B. P. Abbott, R. Abbott, T. D. Abbott, M. R. Abernathy, F. Acernese, K. Ackley, C. Adams, T. Adams, P. Addesso, R. X. Adhikari, V. B. Adya, C. Affeldt, M. Agathos, K. Agatsuma, N. Aggarwal, O. D. Aguiar, L. Aiello, A. Ain, P. Ajith, B. Allen, A. Allocca, P. A. Altin, S. B. Anderson, W. G. Anderson, K. Arai, M. C. Araya, C. C. Arceneaux, J. S. Areeda, N.(More)
We report the observation of a gravitational-wave signal produced by the coalescence of two stellar-mass black holes. The signal, GW151226, was observed by the twin detectors of the Laser Interferometer Gravitational-Wave Observatory (LIGO) on December 26, 2015 at 03:38:53 UTC. The signal was initially identified within 70 s by an online matched-filter(More)
J. Abadie, B. P. Abbott, R. Abbott, T. D. Abbott, M. Abernathy, T. Accadia, F. Acernese, C. Adams, R. Adhikari, C. Affeldt, M. Agathos, K. Agatsuma, P. Ajith, B. Allen, E. Amador Ceron, D. Amariutei, S. B. Anderson, W.G. Anderson, K. Arai, M.A. Arain, M. C. Araya, S.M. Aston, P. Astone, D. Atkinson, P. Aufmuth, C. Aulbert, B. E. Aylott, S. Babak, P. Baker,(More)
On 14 September 2015, a gravitational wave signal from a coalescing black hole binary system was observed by the Advanced LIGO detectors. This paper describes the transient noise backgrounds used to determine the significance of the event (designated GW150914) and presents the results of investigations into potential correlated or uncorrelated sources of(More)
J. Aasi, J. Abadie, B. P. Abbott, R. Abbott, T. D. Abbott, M. Abernathy, T. Accadia, F. Acernese, C. Adams, T. Adams, P. Addesso, R. Adhikari, C. Affeldt, M. Agathos, K. Agatsuma, P. Ajith, B. Allen, A. Allocca, E. Amador Ceron, D. Amariutei, S. B. Anderson, W.G. Anderson, K. Arai, M. C. Araya, S. Ast, S.M. Aston, P. Astone, D. Atkinson, P. Aufmuth, C.(More)
The gravitational-wave signal GW150914 was first identified on September 14, 2015, by searches for short-duration gravitational-wave transients. These searches identify time-correlated transients in multiple detectors with minimal assumptions about the signal morphology, allowing them to be sensitive to gravitational waves emitted by a wide range of sources(More)
Transcription-associated recombination is an important process involved in several aspects of cell physiology. In the ribosomal DNA (rDNA) of Saccharomyces cerevisiae, RNA polymerase II transcription-dependent recombination has been demonstrated among the repeated units. In this study, we investigate the mechanisms controlling this process at the chromatin(More)
Histone deacetylases (HDAC) are key enzymes in the epigenetic control of gene expression. Recently, inhibitors of class I and class II HDAC have been successfully employed for the treatment of different inflammatory diseases such as rheumatoid arthritis, colitis, airway inflammation and asthma. So far, little is known so far about a similar therapeutic(More)
The discovery of the gravitational-wave (GW) source GW150914 with the Advanced LIGO detectors provides the first observational evidence for the existence of binary black hole (BH) systems that inspiral and merge within the age of the universe. Such BH mergers have been predicted in two main types of formation models, involving isolated binaries in galactic(More)