Eliot Slater

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In this short book, which is the first of its kind to appear, the authors have described the various physical treatments for psychiatric disorders which have been developed in the last 20 years. Much of the working principles and details that are provided, are not otherwise available in book form. The insulin treatment of schizophrenia, convulsion therapy,(More)
Effects of the L-type calcium channel antagonist diltiazem on recombinant human GABA(A) receptor (alpha1beta2gamma2s) or on muscle (alpha1beta1deltagamma and alpha1beta1delta(epsilon)) or neuronal (alpha7 and alpha4beta2) nicotinic acetylcholine receptors expressed in Xenopus oocytes were examined using two-electrode voltage-clamp. Diltiazem inhibited the(More)
Since the classic descriptions of the course of bipolar and recurrent depressive forms of manic-depressive illness by Emil Kraepelin a century ago, it has been considered a truism that the rate of cycling increases, and wellness intervals shorten, with rising counts of recurrences, particularly early in the natural history of the illness. Less well known is(More)
(S)-Aporphine metho salts with the 1,2,9,10 oxygenation pattern displaced radioligands from recombinant human alpha7 and alpha4beta2 neuronal nicotinic acetylcholine receptors (nAChR) at low micromolar concentrations. The affinity of the nonphenolic glaucine methiodide (4) (vs [(3)H]cytisine) was the lowest at alpha4beta2 nAChR (K(i)=10 microM), and(More)
find the ictal depressions, along the side BC oneirophrenia, and along the side CA the schizo-affective psychoses. Investigating the families of patients suffering from atypical schizophrenic illnesses, Mitsuda finds psychotic states of a heterogeneous kind, typical and atypical schizophrenias, affective illnesses and epilepsy, a raised incidence of(More)
In so far as a mental analysis of the feasibility of a machine to "play" Chess may assist us to decide more clearly what true constructive thought is and whether brains in principle are differ&t from machines, I wholeheartedly support such work. I feel however that the actual construction of such a machine in all its relatively vast complexity apart from(More)
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