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BACKGROUND The usefulness of induced sputum in searching for causative agents of pneumonia in children has not been studied. METHODS The study involved 101 children, aged 6 months to 15 years, treated for community-acquired pneumonia at Turku University Hospital (Turku, Finland) from January 2006 to April 2007. Nasopharyngeal aspirate samples were first(More)
Few comprehensive studies have searched for viruses and bacteria in children with community-acquired pneumonia (CAP). We identified 76 children hospitalized for pneumonia. Induced sputum samples were analysed for 18 viruses by antigen detection and PCR, and for six bacteria by culture and PCR. Viruses were found in 72% of samples, bacteria in 91%, and both(More)
AIM The aim of the study was to find clinical predictors for parapneumonic empyema in children. METHODS Thirty-seven children treated for parapneumonic empyema at the Department of Pediatrics, Turku University Hospital, were retrospectively evaluated. Two distinct comparison groups of children with uncomplicated community-acquired pneumonia with alveolar(More)
OBJECTIVES To understand relationships between microbes in pathogenesis of acute otitis media during respiratory tract infections, we compared nasopharyngeal bacteria and respiratory viruses in symptomatic children with and without AOM. METHODS We enrolled children (6-35 months) with acute symptoms suggestive of AOM and analyzed their nasopharyngeal(More)
BACKGROUND Influenza and pneumonia are common childhood illnesses, but few studies have been conducted on influenza-related pneumonia in children. The aim of this study was to describe the frequency and characteristics of laboratory-documented and radiologically detected influenza pneumonia in children. METHODS This study involved children treated at the(More)
BACKGROUND Tympanometry can indicate middle ear effusion in children referred for tympanostomy tube placement. In outpatient setting, objective adjunctive tools are needed to diagnose the otitis media spectrum. METHODS We enrolled and followed 515 children aged 6-35 months at primary care level. We compared tympanometry with pneumatic otoscopy and(More)
BACKGROUND Obtaining a nasal swab (NS) from a child for human rhinovirus (HRV) RNA detection is simple and well tolerated even for repeated sampling, but only few studies have compared them qualitatively and quantitatively with other sampling methods. OBJECTIVES Real-time PCR was used to study the stability of HRV genomes in swabs, and to compare(More)
BACKGROUND The incidence of parapneumonic empyema in children has increased worldwide, but the long-term anatomical and functional consequences in the lungs after empyema are not known. METHODS We investigated the long-term outcome of childhood empyema in 26 patients by physical examination, chest radiograph and magnetic resonance image (MRI) of the(More)
We present a case of severe pneumonia, associated with a prolonged infection by a species C rhinovirus (HRV) in a 3-week old neonate. HRV RNA was identified in nasal and nasopharyngeal secretions, bronchoalveolar lavage and bronchial specimens, stool and urine, collected from the patient during a one-month period. No other viral or bacterial agents were(More)
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