Elina A. Genina

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The development of optical methods in modern medicine in the areas of diagnostics, therapy, and surgery has stimulated the investigation of optical properties of various biological tissues, since the e±cacy of laser treatment depends on the photon propagation and °uence rate distribution within irradiated tissues. In this work, an overview of published(More)
An in vitro experimental study of the control of the human dura mater optical properties at administration of aqueous solutions of glucose and mannitol has been presented. The significant increase of the dura mater optical transmittance under action of immersion liquids has been demonstrated. Diffusion coefficients of glucose and mannitol in the human dura(More)
Near infrared (NIR) diode laser low-intensity (soft) phototherapy with the topical application of indocyanine green (ICG) has been suggested for treatment of acne vulgaris. Twelve volunteers with acne lesions on their faces and/or backs were enrolled in the experiment. Skin areas of the subjects that were 4 x 5 cm2 were stained with ICG solution for 5 min(More)
In this article, we discuss the optical immersion method based on refractive index matching of scatterers (e.g., collagen, elastin fibers, cells and cell compartments) and the ground material (interstitial fluid and/or cytoplasm) of tissue and blood under the action of exogenous optical clearing agents. We analyze the optical clearing of fibrous and(More)
AIM Urinary iodine excretion (UIE) provides information about iodine supply and release. In the present study we investigated effects of the application of different radioiodine isotopes on UIE in patients with differentiated thyroid carcinoma (DTC). PATIENTS, METHODS In 91 consecutive patients with DTC UIE, measured as iodine/creatinine ratio, was(More)
BACKGROUND AND OBJECTIVES The near-infrared (NIR) laser radiation due to its high penetration depth is widely used in phototherapy. In application to skin appendages, a high selectivity of laser treatment is needed to prevent light action on surrounding tissues. Indocyanine green (ICG) dye may provide a high selectivity of treatment due to effective ICG(More)
We present experimental results on the in vitro and in vivo study of dye diffusion into human skin and hair follicles. We have studied some commercially available dyes for potential using in the laser selective thermolysis. The degree and the depth of hair follicle dyeing inside the skin were determined. For hairs in different stages the sebaceous gland was(More)
The optical properties of human cranial bones were measured in the wavelength range 800-2000 nm. The measurements were carried out using the commercially available spectrophotometer with an integrating sphere. The inverse addingdoubling method was used to determine the absorption and reduced scattering coefficients from the measurements.
Accelerated diffusion of water and hyperosmotic optical clearing agents is studied as a result of enhanced epidermal permeability. A lattice of microzones (islets) of damage in stratum corneum is induced using a flash-lamp applique system. An optical clearing agent composed of 88% glycerol in aqueous solution is used for all experiments. Research of skin(More)
Mie based theoretical analysis has been performed for investigation of the possibility of application of the plasma hemoglobin releasing due to local hemolysis for optical clearing of blood. The 30-40% reduction of the scattering coefficient of blood in the spectral range from 400 to 1000 nm with increase of degree of hemolysis (up to 20%) was shown. At the(More)