Elias Bjornson

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To investigate the biological processes that are altered in obese subjects, we generated cell-specific integrated networks (INs) by merging genome-scale metabolic, transcriptional regulatory and protein-protein interaction networks. We performed genome-wide transcriptomics analysis to determine the global gene expression changes in the liver and three(More)
Recent studies conducted in the United Kingdom show that 33% to 46% of women report decreased sexual response after hysterectomy-oophorectomy. The prevailing theory in the United States for over 30 years in counseling women is that such decreases are infrequent and, if they do occur, are psychogenic. The postulates of the psychogenesis theory were examined(More)
To elucidate the molecular mechanisms underlying non-alcoholic fatty liver disease (NAFLD), we recruited 86 subjects with varying degrees of hepatic steatosis (HS). We obtained experimental data on lipoprotein fluxes and used these individual measurements as personalized constraints of a hepatocyte genome-scale metabolic model to investigate metabolic(More)
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