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  • Ronan Le Goffic, Julien Pothlichet, +4 authors Mustapha Si-Tahar
  • Biology, Medicine
  • The Journal of Immunology
  • 2007 (First Publication: 15 March 2007)
  • Influenza A virus (IAV) triggers a contagious acute respiratory disease that causes considerable mortality annually. Recently, we established a role for the pattern-recognition TLR3 in the responseExpand
  • Rongtuan Lin, J. Lacoste, +8 authors J. Hiscott
  • Medicine, Biology
  • Journal of Virology
  • 2006 (First Publication: 15 June 2006)
  • ABSTRACT Intracellular RNA virus infection is detected by the cytoplasmic RNA helicase RIG-I that plays an essential role in signaling to the host antiviral response. Recently, the adapter moleculeExpand
  • Marion C. Bonnet, Robert Weil, Elisabeth Dam, Ara G. Hovanessian, Eliane F. Meurs
  • Medicine, Biology
  • Molecular and Cellular Biology
  • 2000 (First Publication: 1 July 2000)
  • ABSTRACT The interferon (IFN)-induced double-stranded RNA-activated protein kinase PKR mediates inhibition of protein synthesis through phosphorylation of the α subunit of eukaryotic initiationExpand
  • G. Clerzius, Jean-François Gélinas, A. Daher, M. Bonnet, E. Meurs, A. Gatignol
  • Biology, Medicine
  • Journal of Virology
  • 2009 (First Publication: 15 July 2009)
  • ABSTRACT The interferon-induced protein kinase RNA activated (PKR) is activated after virus infection. This activation is transient during the human immunodeficiency virus type 1 (HIV-1) infection ofExpand