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1005 Background: B in combination with weekly paclitaxel or docetaxel (D) as 1st-line therapy for MBC has improved progression-free survival (PFS) compared with the respective taxane alone in two large Phase III trials. This study investigated the addition of B to standard 1st-line chemotherapy regimens for MBC. METHODS Patients were randomized in 2:1(More)
The interferon-gamma release assays have greater specificity than the tuberculin skin test (TST), and at least equal sensitivity. We analyzed the sensitivity and specificity of the TST in immunocompetent children considering QuantiFERON as the referent standard. A TST cut-off point of ≥ 5 mm indicates excellent sensitivity (100%) and specificity (93%) in(More)
AIMS To compare the QuantiFERON-TB GOLD In Tube test (QTF) and the tuberculin skin test (TST) in children. METHODS A prospective study was carried out in nine hospitals in Madrid, Spain. TST and QTF were performed in immigrants, tuberculosis (TB) contacts and patients with TB disease (TBD). RESULTS 459 children were included. Disagreement between the(More)
OBJECTIVE To determine the frequency of adverse drug reactions in surgical intensive care units and evaluate their effect on the length of stay. DESIGN Prospective cohort study. Between May 1997 and December 1999, while the patients were staying in the surgical intensive care unit, data were gathered regarding suspected adverse drug reactions and on(More)
Investigation of the combination of the taxanes with doxorubicin in the treatment of breast cancer has logically progressed, with the ultimate goal of identifying a safe and effective regimen for use in the adjuvant setting. Initial phase II findings of the concurrent doxorubicin/paclitaxel combination resulted in substantial response rates, but at a high(More)
PURPOSE The purpose of this article is to describe the process of implementing Nursing Grand Rounds in a community hospital. METHODS The Advanced Practice Council of clinical nurse specialists and nurse practitioners used Benner's theoretical framework of skill acquisition to guide the process. The development and implementation included the following:(More)
The relationship between the IgM antibody response, antigenic load as well as the clinical improvement after chemotherapy was studied in order to obtain useful data for the early diagnosis and monitoring leprosy. A level of 82% (94/115) agreement was obtained between IgM UMELISA HANSEN and slit-skin smear examination. Discrepant results were observed in 16(More)
BACKGROUND AND OBJECTIVE Women with polycystic ovary syndrome (PCOS) exhibit frequently risk factors that predispose to cardiovascular disease. Hyperhomocysteinemia is an independent risk factor for this disease. The aim of this study was to know whether young women with PCOS have increased homocysteine levels. We also analyzed their possible relation with(More)
In this paper a dialogue system with spoken Spanish and computer vision that plays the game “Guess the card” with members of the general public in a permanent stand of the science museum Universum at the National Autonomous University of Mexico (UNAM) is presented. The conceptual and architectural guidelines for the construction of the system are presented.(More)
This article reports on a study which reviewed the utilization of six adult psychiatric day hospitals in a Canadian urban region. Part II of the study looks at the utilization patterns of these services through the examination of patients' demographics and clinical characteristics. The application of the study results to the planning of psychiatric services(More)