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Evaluating interface usability and system functionality is time-consuming and effort-intense. The short time-span involved in development iterations, such as those in agile development, makes it challenging for software teams to perform ongoing interface usability evaluation and system functionality testing. We propose a way to perform <i>product ongoing(More)
It has been found that some macrocyclic esters have no ionophoric properties, but can block valinomycin-induced potassium transport in mitochondrial membranes and lessen the potassium current induced by valinomycin in phosphatidylcholine bilayers. It has been also discovered that 36-member cyclic esters of succinic acid and propylene glycoles decrease(More)
Several papers have indicated the participation of cyclic AMP as a second messenger for the release of neurohypophysial hormones. Since very little is known about the effects of stress and drugs of abuse on this process, we studied the activity of adenylyl cyclase in the neurohypophyses after immobilization stress and chronic amphetamine treatment. Our(More)
A study was made of physiological activity of a series of new bisquaternary compounds in which the role of cation heads is played by the residues of 2-amino-1,3-diazepinium. Studies performed on a frog neuromuscular preparation showed that the compounds under test effectively block the responses of the postsynaptic membrane to acetylchinoline. The(More)
The new psychotropic drug phenazepam inhibits the impulse activity of the neurons which compose visceral ganglia of the garden snail (Helix aspersa) and suppresses stimulating postsynaptic potentials arising in application of acetylcholine to the membrane of isolated neurons. The electrostimulating membrane parameters are not generally changed. Postsynaptic(More)
The mechanism of tonic component of the frog myocardium potassium contraction was studied. The degree of contraction depended on the potassium, sodium and calcium ions concentrations in extracellular medium. The tonic component of hyperpotassium contraction, as well as the additional contractions due to hyposodium and hypercalcium medium in the tonic(More)