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Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core
Lipid nanoparticles (LNP) containing ionizable cationic lipids are the leading systems for enabling therapeutic applications of siRNA; however, the structure of these systems has not been defined.Expand
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Correction to “Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core”
A mistake has been found in the article on page 18444. The second paragraph should read: “Here we explored whether limit size particles compatible with such structures could be generated usingExpand
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Simulation Study on the Properties of Cationic Lipid Bilayers and Vesicles
We are using molecular dynamics simulations to investigate the properties of ionizable cationic lipids forming bilayers and vesicles. This is important for rational design of lipid nanoparticle forExpand
Computer Simulations of the Interactions Between Cationic and Anionic Lipids in Lipid Nano Particles for Drug Delivery
We used molecular dynamics simulation to investigate the structure and properties of lipid nanoparticles (LNP), with as long-term goal improving the efficiency of delivery of nucleic acids in geneExpand