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Cytogenetic activity of diazepam in normal human lymphocyte cultures.
INTRODUCTION Diazepam (DZ) belongs to benzodiazepines, a group of drugs used for sedation, for the relief of anxiety, and in the treatment of epilepsy. It has been found that DZ influences cytotoxicExpand
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Changes In TNF-Alpha Levels, Microcirculation Status, And Oxidation Products After Liver Ischemia/Reperfusion Injury In Mice
Purpose: Experimental study to determine the role of TNF-α in the pathogenesis of oxidative damage in the liver induced by ischaemia reperfusion. Methods: 50 Wistar rats in five groups of 10 each,Expand
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Comparison of new nitrosoureas esters with modified steroidal nucleus for cytogenetic and antineoplastic activity.
Nitrosourea is decomposed under physiological conditions to react with biological macromolecules by two mechanisms: alkylation (with proteins and nucleic acids) and carbamoylation (with proteins butExpand
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Changes in Activities of Caspase-8 and Caspase-9 in Human Cervical Malignancy
Introduction The apoptotic process of programmed cell death and its dysfunctions in a variety of human diseases, including cervical cancer, has become the focus of extensive scientific research.Expand
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A comparative study of the cytogenetic and antineoplastic effects induced by steroidal amidoesters of p-N, N-bis (2-chloroethyl) aminophenylbutyric acid (chlorambucil)
L'effet de quatre stereoisomers d'amidoesters steroidaux avec de l'acide p-N, N-bis (2-chloroethyl) aminophenylbutyric (chlorambucil) sur les echanges de chromatides soeur (SCE) et sur les cinetiquesExpand
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