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Cytogenetic activity of diazepam in normal human lymphocyte cultures.
- K. Akritopoulou, Z. Iakovidou-Kritsi, E. Mioglou-Kalouptsi, Maria T. Ekonomopoulou, D. Mourelatos
- Biology, Medicine
- Genetic testing and molecular biomarkers
- 17 April 2009
INTRODUCTION Diazepam (DZ) belongs to benzodiazepines, a group of drugs used for sedation, for the relief of anxiety, and in the treatment of epilepsy. It has been found that DZ influences cytotoxic… Expand
Changes In TNF-Alpha Levels, Microcirculation Status, And Oxidation Products After Liver Ischemia/Reperfusion Injury In Mice
Purpose: Experimental study to determine the role of TNF-α in the pathogenesis of oxidative damage in the liver induced by ischaemia reperfusion. Methods: 50 Wistar rats in five groups of 10 each,… Expand
Comparison of new nitrosoureas esters with modified steroidal nucleus for cytogenetic and antineoplastic activity.
Nitrosourea is decomposed under physiological conditions to react with biological macromolecules by two mechanisms: alkylation (with proteins and nucleic acids) and carbamoylation (with proteins but… Expand
Changes in Activities of Caspase-8 and Caspase-9 in Human Cervical Malignancy
- Maria T. Ekonomopoulou, Evaggelos Babas, E. Mioglou-Kalouptsi, M. Malandri, Z. Iakovidou-Kritsi
- International Journal of Gynecologic Cancer
- 26 December 2010
Introduction The apoptotic process of programmed cell death and its dysfunctions in a variety of human diseases, including cervical cancer, has become the focus of extensive scientific research.… Expand
A comparative study of the cytogenetic and antineoplastic effects induced by steroidal amidoesters of p-N, N-bis (2-chloroethyl) aminophenylbutyric acid (chlorambucil)
L'effet de quatre stereoisomers d'amidoesters steroidaux avec de l'acide p-N, N-bis (2-chloroethyl) aminophenylbutyric (chlorambucil) sur les echanges de chromatides soeur (SCE) et sur les cinetiques… Expand