Eleonora Dyakova

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Skeletal muscle cells secrete a variety of hormones and cytokines, which are referred to as myokines. Different modes of exercise are the main factor of myokines producing. The myokines expression level is increased in an exponential fashon proportional to the length of exercise and the amount of muscle mass engaged in the exercise. These myokines are(More)
BACKGROUND Carbapenemase-producing Enterobacteriaceae (CPE) are an emerging threat for healthcare providers worldwide. OBJECTIVES To determine CPE carriage rates and risk factors in an unselected hospital cohort at the time of admission. METHODS We approached 4567 patients within 72 h of admission to provide a rectal swab and answer a questionnaire on(More)
OBJECTIVES We evaluated 'pre-laboratory' factors associated with the detection of extended spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) colonization including anatomical site, and staff and patient factors. METHODS All admissions to a large London hospital over 3 months were approached to provide rectal and perineal swabs, which were(More)
The clinical impact of implementing hydrogen peroxide vapour (HPV) disinfection of rooms vacated by patients with Clostridium difficile infection (CDI) was evaluated. Breakpoint time series analysis indicated a significant reduction (P<0.001) in the CDI rate at the time when HPV disinfection was implemented, resulting in a reduction in the CDI rate from 1.0(More)
Carbapenemase-producing Enterobacteriaceae (CPE) are emerging worldwide, limiting therapeutic options. Mutational and plasmid-mediated mechanisms of colistin resistance have both been reported. The emergence and clonal spread of colistin resistance was analysed in 40 epidemiologically-related NDM-1 carbapenemase producing Klebsiella pneumoniae isolates(More)
OBJECTIVE To estimate the isolation demands arising from high-risk specialty-based screening for carbapenemase-producing Enterobacteriaceae (CPE), and the potential fraction of CPE burden detected. METHODS Clinical specialty groups from three London hospitals were ranked by incidence of carbapenem resistance among Escherichia coli and Klebsiella spp.(More)
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