Eleonora Colantoni

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The importance of autophagy in mechanisms underlying inflammation has been highlighted. Downstream effects of the bacterial sensor NOD2 include autophagy induction. Recently, a relationship between defects in autophagy and adherent/invasive Escherichia coli (AIEC) persistence has emerged. The present study aims at investigating the interplay between(More)
G. Capacchietti1, S. Cecconi2, E. Colantoni2, V. Russo1, P. Berardinelli1, B. Barboni1 and M. Mattioli1 1Dip. Scienze Biomediche Comparate, Università degli Studi di T eramo; 2Dip. Scienze e T ecnologie Biomediche,Università degli Studi di L ’Aquila *Correspondence: Dip. Scienze Biomediche Comparate, sezione Fisiologia, Facoltà di Medicina Veterinaria,(More)
BACKGROUND Necroptosis is an inflammatory form of programmed cell death requiring receptor-interacting protein kinase 3 (RIP3) and mixed lineage kinase domain-like protein (MLKL). AIMS The aim of this study is to examine in depth in vitro and ex vivo the contribution of necroptosis to intestinal inflammation. METHODS In vitro: we used an intestinal cell(More)
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