Elena Savelieva

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CDKN2/p16 inhibits the cyclin D/cyclin-dependent kinase complexes that phosphorylate pRb, thus blocking cell cycle progression. We previously reported that p16 levels are low to undetectable in normal human uroepithelial cells (HUCs) and in immortalized uroepithelial cells with functional pRb, whereas p16 levels are markedly elevated in immortal HUCs with(More)
Direct Neural Network Residual Kriging (DNNRK) is a two step algorithm (Kanevsky et al. 1995). The first step includes estimating large scale structures by using artificial neural networks (ANN) with simple sum of squares error function. ANN, being universal approximators, model overall non-linear spatial pattern fairly well. ANN are model free estimators(More)
Neural cell adhesion molecule (NCAM) is down-regulated during periods of embryological cell migration and may be important in local tumor migration or metastases. Conflicting information exists in the literature about NCAM expression in human glial tumors and little is known about its expression in human brain metastases. We immunohistochemically stained a(More)
897,.9 The work is devoted to an application of artificial neural network (multilayer perceptron) and conditional stochastic simulations to electricity load forecasting in Russia. One of the problems is missing data and some important weather parameters (wind, cloudiness, precipitation, historical information). This gives rise to rather large forecasting(More)
CDKN2/pl6 inhibits the cyclin D/cyclin-dependent kinase complexes that phosphorylate pRb, thus blocking cell cycle progression. We previ ously reported that pl6 levels are low to undetectable in normal human uroepithelial cells (III (si and in immortalized uroepithelial cells with functional pRb, whereas pl6 levels are markedly elevated in immortal HUCs(More)
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