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Glutamine deamidation: an indicator of antiquity, or preservational quality?
RATIONALE Much credence has been given in the paleoproteomic community to glutamine deamidation as a proxy for the age of proteins derived from fossil and subfossil material, and this modificationExpand
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Molecular evidence of keratin and melanosomes in feathers of the Early Cretaceous bird Eoconfuciusornis
Significance We report fossil evidence of feather structural protein (beta-keratin) from a 130-My-old basal bird (Eoconfuciusornis) from the famous Early Cretaceous Jehol Biota, which has producedExpand
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Bone protein “extractomics”: comparing the efficiency of bone protein extractions of Gallus gallus in tandem mass spectrometry, with an eye towards paleoproteomics
Proteomic studies of bone require specialized extraction protocols to demineralize and solubilize proteins from within the bone matrix. Although various protocols exist for bone protein recovery,Expand
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Biologically and diagenetically derived peptide modifications in moa collagens
The modifications that occur on proteins in natural environments over time are not well studied, yet characterizing them is vital to correctly interpret sequence data recovered from fossils. TheExpand
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Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis.
Structures similar to blood vessels in location, morphology, flexibility, and transparency have been recovered after demineralization of multiple dinosaur cortical bone fragments from multipleExpand
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Expansion for the Brachylophosaurus canadensis Collagen I Sequence and Additional Evidence of the Preservation of Cretaceous Protein.
Sequence data from biomolecules such as DNA and proteins, which provide critical information for evolutionary studies, have been assumed to be forever outside the reach of dinosaur paleontology.Expand
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The molecular evolution of feathers with direct evidence from fossils
Significance During the dinosaur–bird transition, feathers of bird ancestors must have been molecularly modified to become biomechanically suitable for flight. We report molecular moieties in fossilExpand
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Paleoproteomics of Mesozoic Dinosaurs and Other Mesozoic Fossils
Molecular studies have contributed greatly to our understanding of evolutionary processes that act upon virtually every aspect of living organisms. However, these studies are limited with regard toExpand
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A Comparison of Common Mass Spectrometry Approaches for Paleoproteomics.
The last two decades have seen a broad diversity of methods used to identify and/or characterize proteins in the archeological and paleontological record. Of these, mass spectrometry has opened anExpand
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Peptide sequences from the first Castoroides ohioensis skull and the utility of old museum collections for palaeoproteomics
Vertebrate fossils have been collected for hundreds of years and are stored in museum collections around the world. These remains provide a readily available resource to search for preservedExpand
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