Elena Kushnareva

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Process-aware information systems (PAIS) supporting knowledge-intensive processes are gaining importance nowadays. Crisis management process is an example of a knowledge-intensive process that is grounded on vast experience of multiple actors (e.g., city services, volunteers, administration) and their collaboration. Automated crisis management systems have(More)
Knowledge and experience of a case manager re- mains a key success factor for Case Management Processes (CMPs). When a number of influential parameters is high, a number of possible scenarios grows significantly. Automated guidance in scenario evaluation and activity planning would be of a great help. In our previous work, we defined the statecharts(More)
Future developments for case management must evolve from the current systems based on rigid, workflow based processes into context-aware, agile dynamic structures. We propose to combine a declarative approach for process design and the use of formal methods to enable a set of automated techniques for process analysis and validation based on model checking(More)
In two models of depression-like state--"behavioral despair" and experimental dopamine deficit-dependent MPTP-induced depression-like syndrome--as well as in a model of anxiety-depression-like state induced by dipeptidyl peptidase IV inhibitor methionyl-2(s)-cyanopyrrolidine administered in early postnatal period, the symptoms of behavioral depression in(More)
We studied the dynamics of activity of dipeptidyl peptidase IV (DP-IV) and prolyl endopeptidase (PEP) in the frontal cortex, hypothalamus, striatum, nucleus accumbens, and hippocampus of rats with experimental anxiety-depression state induced by administration of methionyl-2(s)-cyano-pyrrolidine, an inhibitor of DPP-IV, in the early postnatal period. In(More)
Administration of a synthetic dipeptidyl peptidase IV inhibitor methionyl-2(S)-cyanopyrrolidine (1 mg/kg) to rats during the early postnatal period was followed by the development of behavioral changes in young and adult animals. The degree of anxiety in the elevated plus maze increased in treated rats at the age of 1-2 months. Depressive behavior in the(More)
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