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CONTEXT Older adults are at risk for greater chronic stress and cognitive decline. Training in mindfulness meditation (MM) may help reduce stress and, thus, cognitive decline in older adults, but little research has explored that hypothesis. OBJECTIVE The current study's primary aim was to evaluate the feasibility and acceptability for use by older adults(More)
Conventional tangential flow filtration (TFF) has traditionally been limited to separation of solutes that differ by about ten-fold in size. Wide pore-size distributions, membrane fouling, and concentration polarization phenomena have commonly been cited as reasons for this limitation. The use of TFF in the biotechnology industry has therefore been(More)
We created a standardized one-on-one mindfulness meditation intervention with six weekly 90-minute training sessions and home practice. The trainings included didactic instruction, discussion and guided meditations, and home-practice guided meditations and mindfulness exercises. Twenty-eight participants completed mindful awareness, nonjudgment, perceived(More)
OBJECTIVE This study's objective was to evaluate the effect of two common components of meditation (mindfulness and slow breathing) on potential mechanistic pathways. METHODS A total of 102 combat veterans with posttraumatic stress disorder (PTSD) were randomized to (a) the body scan mindfulness meditation (MM), (b) slow breathing (SB) with a biofeedback(More)
To determine if mindfulness meditation (MM) in older adults improves cognition and, secondarily, if MM improves mental health and physiology, 134 at least mildly stressed 50-85 year olds were randomized to a six-week MM intervention or a waitlist control. Outcome measures were assessed at baseline and two months later at Visit 2. The primary outcome measure(More)
OBJECTIVE This cross-sectional study evaluated event-related potentials (ERPs) across three groups: naïve, novice, and experienced meditators as potential physiological markers of mindfulness meditation competence. METHODS Electroencephalographic (EEG) data were collected during a target tone detection task and a Breath Counting task. The Breath Counting(More)
People with severe speech and physical impairments may benefit from mindfulness meditation training because it has the potential to enhance their ability to cope with anxiety, depression and pain and improve their attentional capacity to use brain-computer interface systems. Seven adults with severe speech and physical impairments (SSPI) - defined as speech(More)
Tangential flow filtration has traditionally been scaled up by maintaining constant the filtrate volume to membrane surface area ratio, membrane material and pore size, channel height, flow path geometry and retentate and filtrate pressures. Channel width and the number of channels have been increased to provide increased membrane area. Several other(More)
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