Elena Devyatko

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GRUNDLAGEN: Die gastroösophageale Refluxkrankheit (GERD) betrifft etwa 20–40% der Bevölkerung in Europa und den USA. Sie ist mit Verlust der Lebensqualität, Ösophagusfunktion und Änderung der Morphologie assoziiert. METHODIK: Übersicht mit level of evidence III–IV Arbeiten über GERD-Diagnostik. ERGEBNISSE: GERD-Symptome (Sodbrennen, Aufstoßen,(More)
HINTERGRUND: In der Endoskopie beginnt der Magen mit den sogenannten gastralen Schleimhautfalten. Anatomische Studien lassen jedoch vermuten, dass diese Falten zum Ösophagus gehören. Deshalb hat diese Studie die Histologie des Beginns der endoskopisch sichtbaren Magenfalten bei Patienten mit gastroösophagealer Refluxkrankheit untersucht. METHODIK: Bei 35(More)
BACKGROUND Surgical methods for treatment of tricuspid valve (TV) endocarditis include complete TV excision, TV replacement, and the use of various reconstructive techniques even in cases of severe TV destruction and incompetence. This study summarizes our experience with TV reconstruction and replacement in patients with severe TV endocarditis. METHODS(More)
BACKGROUND Cytomegalovirus (CMV) has long been recognized as the most common opportunistic pathogen in transplant recipients. The use of post-detection antiviral treatment of CMV as a strategy to prevent disease in cardiac recipients is becoming the standard policy. Valganciclovir is an oral pro-drug of ganciclovir, with a 10-fold greater bioavailability(More)
OBJECTIVE To compare survival of patients with isolated synchronous and metachronous brain metastases from non-small cell lung cancer (NSCLC) after combined surgical treatment. METHODS A total of 991 patients underwent surgical resection of primary NSCLC between January 1994 and November 1999. Out of these, 32 patients (21 males and 11 females) were(More)
This study assessed the value of haemostatic fleece (HF) in prevention of pleural adhesions in an experimental animal model. Forty rats were randomly assigned to four equal groups and underwent bilateral thoracotomy. In Group 1 standardized defects of 5 mm were generated in the visceral and the opposite parietal pleura without further coverage. In Group 2 a(More)
BACKGROUND The objective of this study was to investigate purine nucleotide metabolism in peripheral blood mononuclear cells (PBMC) of cardiac transplant recipients switched from azathioprine to mycophenolate mofetil (MMF). METHODS Concentrations of guanosine 5'triphosphate (GTP) and adenosine 5'triphosphate (ATP), the activities of inosine monophosphate(More)
BACKGROUND In an attempt to monitor the pharmacodynamics of mycophenolate mofetil (MMF) we investigated the association of inosine monophosphate dehydrogenase (IMPDH) activity in peripheral blood mononuclear cells with the expression of lymphocyte activation markers in stable cardiac transplant recipients treated with MMF. METHODS Twenty-four study(More)
BACKGROUND Our aim was to study the process of microcirculatory reconstitution in the bronchial stump after pneumonectomy. METHODS Eighteen juvenile pigs (median weight 40.6 kg) were randomly assigned to three groups. In all animals left pneumonectomy was performed and the stapled bronchial stump (median length 3.8 cm) carefully denuded. Group I animals(More)
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