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  • Stephen J White, Elaine M Hayes, Stéphanie Lehoux, Jamie Y. Jeremy, Anton J. G. Horrevoets, Andrew C. Newby
  • Medicine, Biology
  • Journal of cellular physiology
  • 2011 (First Publication: 1 November 2011)
  • Most acute coronary events occur in the upstream region of stenotic atherosclerotic plaques that experience laminar shear stress (LSS) elevated above normal physiological levels. Many studies haveContinue Reading
  • Elaine M Hayes, Aikaterini Tsaousi, +6 authors Andrew C Newby
  • Biology, Medicine
  • Front. Immunol.
  • 2014 (First Publication: 28 October 2014)
  • BACKGROUND Rupture of advanced atherosclerotic plaques accounts for most life-threatening myocardial infarctions. Classical (M1) and alternative (M2) macrophage activation could promoteContinue Reading
  • Aikaterini Tsaousi, Elaine M Hayes, +5 authors Elena Aikawa
  • Medicine, Biology
  • PloS one
  • 2016 (First Publication: 17 February 2016)
  • BACKGROUND Thelper1 (Th1) lymphocytes have been previously implicated in atherosclerotic plaque growth but their role in plaque vulnerability to rupture is less clear. We investigated whether T-betContinue Reading