Elaine Graham Sinclair

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Agreement problems are central to the study of wait-free protocols for shared memory distributed systems. We examine two speciic issues arising out of this study. We consider the complexity of the wait-free approximate agreement problem in an asyn-chronous shared memory comprised of only single-bit multi-writer multi-reader registers. For real-valued inputs(More)
Mutations in the p53 tumor-suppressor gene are prevalent in human cancers. The majority of p53 mutations are missense, which can be classified into contact mutations (that directly disrupts the DNA-binding activity of p53) and structural mutations (that disrupts the conformation of p53). Both of the mutations can disable the normal wild-type (WT) p53(More)
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