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AIM The aim of the study was to investigate neutrophil respiratory burst activity (NRBA) in workers who were occupationally exposed to formaldehyde. METHODS NRBA, spontaneous and stimulated with E. coli, N-formyl-methionyl-leucyl-phenylalanine (fMLP) and phorbol 12-myristate 13-acetate (PMA), was studied by means of quantitative flow cytometric(More)
Experiments were conducted on CBA mice. The effect of heparin and of the fraction of human blood plasma precipitated by heparin (FPH) on the course of the specific immunity reaction, i.e. of rosette-formation, was studied. Inhibition of the mentioned reaction by FPH was revealed. No such effect was produced by heparin. Experiments were carried out in vitro.(More)
The effect of heparin and heparin-precipitated fraction of human blood plasma (HPF) on the ability of spleen cells of mice immunized with sheep's red blood cells to form plaques in vitro was studied. Heparin and HPF were found to inhibit plaque formation as a result of interaction with lymphocytes. It is postulated that the possible point of application of(More)
The immune and endocrine systems and HLA genotype were subjected to a comparative study in patients with systemic and discoid lupus erythematosus (SLE, DLE). The patients suffering from these diseases were found to differ in a number of the parameters of the immune status including the content in blood serum and supernatant of the cultivated mononuclear(More)